Results 81 to 90 of about 108,740 (146)

MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation [PDF]

, 2014
This work was funded by the Multiple Sclerosis Society. Tissue samples and associated clinical and neuropathological data were supplied by the UK MS Tissue ...
Kay, O., Reijerkerk, A., Hirst, MC, King-Robson, Josh, de Vries, HE, Michael, G.J., Male, DK, Reijerkerk, A, Reijerkerk, Arie, Sharrack, B, de Vries, Helga E., Romero, I.A., Baker, D., Kay, Oliver, Simpson, Julie E., Simpson, J.E., Romero, IA, Male, D.K., de Vries, H.E., Baker, David, King-Robson, J., Sharrack, B., King-Robson, J, Wu, D., Michael, GJ, Wu, Dongsheng, Wu, D, Simpson, JE, Lopez-Ramirez, Miguel Alejandro, Lopez-Ramirez, MA, Kay, O, Pryce, Gareth, Hirst, M.C., Baker, D, Male, David Kingsley, Romero, Ignacio Andres, Pryce, G, Pryce, G., Hirst, Mark C., Sharrack, Basil, Michael, Gregory J., Lopez-Ramirez, M.A.   +41 more
core   +1 more source

circPDE4B downregulation triggers GEMIN5‑dependent translational stress response and autophagy to reduce MAPT pathology

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Circular RNAs (circRNAs) are emerging as key regulators of gene expression, synaptic plasticity, and neuronal function in Alzheimer's disease (AD). Here, we characterize the biological actions of circPDE4B, a highly expressed circRNA markedly reduced in AD. METHODS circPDE4B knockdown in neuronal progenitor cells was combined with
Sambhavi Puri, Sophie J. F. van der Spek, Mintao Lin, Zihan Wang, Jacob Porter, Junming Hu, Liyuan Hu, Alejandro N. Rondón‐Ortiz, Alexander Knyshov, Jenna L. Libera, Scott E. Counts, Debomoy K. Lahiri, Julia TCW, Andrew Emili, Xiaoling Zhang, Benjamin Wolozin   +15 more
wiley   +1 more source

MicroRNA‐Mediated Regulation of Brain Aging Hallmarks: Implications for Neurodegeneration and Neural Recovery

Brain and Behavior, Volume 16, Issue 5, May 2026.
Hallmarks of brain aging regulated by microRNAs (miRNAs). This graphical abstract illustrates the central role of miRNAs in coordinating key biological processes associated with brain aging. miRNAs regulate multiple interconnected hallmarks, including genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis and impaired ...
Mustafa T. Ardah, Pareshkumar N. Patel, Omayma Salim Waleed, Jamuna K. V., Vandana Tripathi, L. Lakshmi, Rajashree Panigrahi, Manoj Kumar Mishra   +7 more
wiley   +1 more source

MicroRNA-encoded behavior in Drosophila [PDF]

, 2015
The relationship between microRNA (miRNA) regulation and the specification of behavior is only beginning to be explored.We found that mutation of a single miRNA locus (miR-iab4/iab8)inDrosophila larvae affects the animal’s capacity to correct its ...
Jamie Johnston (7583810), Johnston, J, Joao Picao-Osorio (16228022), Berni, J, Matthias Landgraf (37354), Picao-Osorio, J, Landgraf, M, Jimena Berni (7875149), Alonso, CR, Claudio Alonso (4462075)   +9 more
core   +1 more source

Circulating tumour cells (CTCs) in haematological malignancies: Advances in biology and clinical relevance with a focus on multiple myeloma

British Journal of Haematology, Volume 208, Issue 5, Page 1535-1550, May 2026.
Spatial heterogeneity limits the sensitivity of bone marrow biopsies, resulting in false‐negative findings. Circulating tumour cells (CTCs) provide a systemic, stratified monitoring approach, using flow cytometry for high tumour burden and EuroFlow or allele‐specific oligonucleotide PCR (ASO‐PCR) for minimal residual disease to enable early relapse ...
Chin‐Mu Hsu, Jui‐Feng Hsu, Jee‐Fu Huang, Yi‐Chang Liu   +3 more
wiley   +1 more source

MicroRNA-200b expression level is negatively associated with pathological grading in human gliomas

Cancer Management and Research, 2018
Xiangyi Kong,1,2,* Shun Gong,3–5,* Tao Yan,6,* Yi Yang1 1Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, People’s Republic of China; 2Department of Breast Surgical ...
Kong X, Gong S, Yan T, Yang Y
doaj  

REGULATION OF MICRORNA-375 [PDF]

, 2012
MicroRNAs are important regulators of eukaryotic cellular processes and their misregulation is associated with many human diseases. MicroRNA-375, a regulator of insulin secretion in pancreatic beta cells, is misregulated in human type 2 diabetes. The aim
Clark, Elizabeth
core  

Differential roles of the microRNA let-7 in C. elegans tissue development [PDF]

, 2015
The organs and tissues of the human body comprise of an astonishing variety of cells as different in morphology and function as muscle cells and neurons.
Rausch, Magdalene
core   +1 more source

MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II Assembly [PDF]

, 2022
MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II ...
Mark Ziemann (13101363), Sona Samuel (13401462), Isabel Lopez Sanchez (13401465), Michael Gantier (13401468), Diana Stojanovski (13401471), Matthew McKenzie (13084017), Yilin Kang (13401459), Sze Chern Lim (13401456)   +7 more
core  

microRNA-126 affects proliferation of undifferentiated thyroid carcinoma [PDF]

, 2015
microRNA-126 affects proliferation of undifferentiated thyroid ...
A Salajegheh (19562203), RA Smith (7926428), MA Rahman (7722935), AKY Lam (19562206)   +3 more
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