Results 41 to 50 of about 1,318,067 (198)

Mixed active metabolites of the SNP-6 series of novel compounds mitigate metabolic dysfunction-associated steatohepatitis and fibrosis: promising results from pre-clinical and clinical trials

Journal of Translational Medicine
Background Metabolic dysfunction-associated steatohepatitis (MASH) is a growing global health concern with no effective pharmacological treatments. SNP-630, a newly developed synthetic molecule with multiple mechanisms of action, and a mixture of two of ...
Hsin-Tien Ho, Yu-Lueng Shih, Tien-Yu Huang, Wen-Hui Fang, Chang-Hsien Liu, Jung-Chun Lin, Chih-Weim Hsiang, Kai-Min Chu, Cheng-Huei Hsiong, Guan-Ju Chen, Yung-En Wu, Jia-Yu Hao, Chih-Wen Liang, Oliver Yoa-Pu Hu   +13 more
doaj   +1 more source

High performance top gate a-IGZO TFT utilizing siloxane hybrid material as a gate insulator

AIP Advances, 2018
We demonstrated gate insulators (GI) fabricated by solution process with the aim of replacing traditional vacuum processed GI. We selected solution siloxane-based material due to its extremely high thermal resistance, excellent transparency, flexibility,
Chaiyanan Kulchaisit, Juan Paolo Soria Bermundo, Mami N. Fujii, Yasuaki Ishikawa, Yukiharu Uraoka   +4 more
doaj   +1 more source

Potential tactics with vitamin D and certain phytochemicals for enhancing the effectiveness of immune-checkpoint blockade therapies

Exploration of Targeted Anti-tumor Therapy, 2023
Immunotherapy strategies targeting immune checkpoint molecules such as programmed cell death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) are revolutionizing oncology.
Ai Tsuji, Sayuri Yoshikawa, Sae Morikawa, Yuka Ikeda, Kurumi Taniguchi, Haruka Sawamura, Tomoko Asai, Satoru Matsuda   +7 more
doaj   +1 more source

Policy Challenges Related to Biofuel Development in Tanzania Politische Herausforderungen in Bezug auf Biokraftstoffe in Tansania

Africa Spectrum, 2010
Biofuels have recently emerged as a major issue in energy policy, agricultural development and natural resource management. The growing demand for biofuels is being driven by high oil prices, energy security concerns and global climate change.
Hussein Sosovele
doaj  

Gelidiales Are Not Just Agar—Revealing the Antimicrobial Potential of Gelidium corneum for Skin Disorders

Antibiotics, 2022
In recent decades, seaweeds have proven to be an excellent source of bioactive molecules. Presently, the seaweed Gelidium corneum is harvested in a small area of the Portuguese coast exclusively for agar extraction.
Margarida Matias, Susete Pinteus, Alice Martins, Joana Silva, Celso Alves, Teresa Mouga, Helena Gaspar, Rui Pedrosa   +7 more
doaj   +1 more source

High-latitude artificial aurora using the EISCAT high-gain HF facility [PDF]

, 2002
The EISCAT high-frequency (HF) transmitter facility at Ramfjord, Norway, has been used to accelerate F-region electrons sufficiently to excite the oxygen atoms and nitrogen molecules, resulting in optical emissions at 630, 557.7 and 427.8 nm.
Hagfors, T., Holma, H., Honary, F., Isham, B., Jussila, J., Kaila, K., Kavanagh, A. J., Kosch, M. J., McCrea, I. W., Rietveld, M. T., Senior, A.   +10 more
core  

The massive neutron star or low-mass black hole in 2S0921-630 [PDF]

, 2004
We report on optical spectroscopy of the eclipsing Halo LMXB 2S0921-630, that reveals the absorption line radial velocity curve of the K0III secondary star with a semi-amplitude K_2=92.89 +/- 3.84 km/s, a systemic velocity $\gamma$=34.9 +/- 3.3 \kms and ...
Branduardi-Raymont G., C. A. Watson, Chevalier C., D. Steeghs, Frank J., Horne K., J. Casares, Mason K. O., Nelemans G., P. A. Charles, R. I. Hynes, S. C. Shih, Shahbaz T., T. Shahbaz   +13 more
core   +4 more sources

Impacts of perR on oxygen sensitivity, gene expression, and murine infection in Clostridioides difficile 630∆erm

Journal of Bacteriology
Clostridioides difficile infection (CDI), characterized by colitis and diarrhea, afflicts approximately half a million people in the USA every year, burdening both individuals and the healthcare system. C.
Anna L. Gregory, Hailey E. Bussan, Madeline A. Topf, Andrew J. Hryckowian   +3 more
doaj   +1 more source

miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis

Biology Direct
Background MicroRNAs (miRNAs) are critical regulators of cancer progression, prompting our investigation into the specific function of miR-630 in pancreatic cancer stem cells (PCSCs).
Jun Zou, Sha Yang, Chongwu He, Lei Deng, Bangran Xu, Shuai Chen   +5 more
doaj   +1 more source

On Being Alienated [PDF]

, 2007
Articl
Martin, Michael
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