Results 51 to 60 of about 1,317,240 (329)

Policy Challenges Related to Biofuel Development in Tanzania Politische Herausforderungen in Bezug auf Biokraftstoffe in Tansania

open access: yesAfrica Spectrum, 2010
Biofuels have recently emerged as a major issue in energy policy, agricultural development and natural resource management. The growing demand for biofuels is being driven by high oil prices, energy security concerns and global climate change.
Hussein Sosovele
doaj  

Impacts of perR on oxygen sensitivity, gene expression, and murine infection in Clostridioides difficile 630∆erm

open access: yesJournal of Bacteriology
Clostridioides difficile infection (CDI), characterized by colitis and diarrhea, afflicts approximately half a million people in the USA every year, burdening both individuals and the healthcare system. C.
Anna L. Gregory   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

High performance top gate a-IGZO TFT utilizing siloxane hybrid material as a gate insulator

open access: yesAIP Advances, 2018
We demonstrated gate insulators (GI) fabricated by solution process with the aim of replacing traditional vacuum processed GI. We selected solution siloxane-based material due to its extremely high thermal resistance, excellent transparency, flexibility,
Chaiyanan Kulchaisit   +4 more
doaj   +1 more source

Measuring the Implementation of an Ethics Initiative: Child Protection in Scottish Sport [PDF]

open access: yes, 2006
Methodologies for measuring the implementation of social inclusion and ethics in sport frequently draw on social marketing techniques or stage models of health behaviour change. This paper illustrates how a composite model of cultural change in sport can
Brackenridge, CH
core  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

miR-630 as a therapeutic target in pancreatic cancer stem cells: modulation of the PRKCI-Hedgehog signaling axis

open access: yesBiology Direct
Background MicroRNAs (miRNAs) are critical regulators of cancer progression, prompting our investigation into the specific function of miR-630 in pancreatic cancer stem cells (PCSCs).
Jun Zou   +5 more
doaj   +1 more source

State-guided entrepreneurship: A case study [PDF]

open access: yes, 2006
The premise that active engagement by the state in business is crucial for small, developing economies for global competitiveness is based on the assumption that the state has the wherewithal to support such competitiveness.
Shome, Tony
core  

The massive neutron star or low-mass black hole in 2S0921-630 [PDF]

open access: yes, 2004
We report on optical spectroscopy of the eclipsing Halo LMXB 2S0921-630, that reveals the absorption line radial velocity curve of the K0III secondary star with a semi-amplitude K_2=92.89 +/- 3.84 km/s, a systemic velocity $\gamma$=34.9 +/- 3.3 \kms and ...
Branduardi-Raymont G.   +13 more
core   +4 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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