Results 71 to 80 of about 121,206 (264)
This study reveals a novel GC therapy targeting cholesterol homeostasis. Inhibiting the SCAP sterol‐sensing domain causes lethal ER stress via cholesterol accumulation, paradoxically forcing continuous synthesis that triggers ferroptosis. The findings link sterol sensing, metabolic dysregulation, and ferroptosis, establishing an anti‐cancer paradigm ...
Qianqian Xu +17 more
wiley +1 more source
EFFECTS OF IRRADIATION ON THERMAL CONDUCTIVITY OF ALLOY 690 AT LOW NEUTRON FLUENCE
Alloy 690 has been selected as a steam generator tubing material for SMART owing to a near immunity to primary water stress corrosion cracking. The steam generators of SMART are faced with a neutron flux due to the integrated arrangement inside a reactor
WOO SEOG RYU +4 more
doaj +1 more source
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong +13 more
wiley +1 more source
This study examined the chemical composition of Neolitsea aciculata essential oil (NAE) and its biological activities. NAE was obtained by hydrodistillation of N.
Sang Suk Kim +3 more
doaj +1 more source
A room‐temperature vanadium cation exchange strategy is developed to achieve simultaneous structural reconstruction and electronic/defect modulation of ZIF‐67 on nickel foam. The resulting mesoporous V20–Co(OH)2 electrode exhibits superior OER activity with low overpotentials and enhanced lattice oxygen participation.
Yongbeen Kim, Seungwoo Han, Wonyoung Lee
wiley +1 more source
We present a stimulus‐replicating system combining a tactile sensor with a wearable Peltier thermotactile module and concentric electrotactile electrode. Signals encoding pressure and temperature drive the stimulators to reproduce mechano‐thermal cues on the skin. AlN/PDMS encapsulation and SA/LA PSA ensure mechanical compliance and thermal efficiency.
Ey‐In Lee +4 more
wiley +1 more source
Scan‐Path‐ and Initial‐State‐Dependent Superdomain Switching in (111)‐Oriented PZT
Scan trajectory and initial superdomain topology govern polarization switching in (111)‐oriented PZT. Automated AFM writing, pulsing experiments, and interferometric 3D‐PFM show that raster scans reproducibly stabilize ordered Type‐I stripe superdomains with constrained variant selection, whereas spiral trajectories generate frustrated mixed‐variant ...
Rama Vasudevan +11 more
wiley +1 more source
Local existence for a general model of size-dependent population dynamics
We shall investigate a size structured population dynamics with aging and birth functions having general forms. The growth rate we deal with depends not only on the size but also on time.
Nobuyuki Kato, Hiroyuki Torikata
doaj +1 more source
An alcohol‐adduct‐mediated strategy is employed to stabilize tin isopropoxide for the formation of a homogeneous double electron transport layer (ETL) incorporating SnO2 nanoparticles (NPs). This double‐ETL exhibits improved optical and charge‐transport properties due to reduced defect density and better energy level alignment, resulting in high ...
You‐Hyun Seo +10 more
wiley +1 more source
The characteristics of patients with anal fistula cancer included a higher proportion of men, younger age, more smokers, and tumor‐related characteristics, including more advanced local progression. Surgical characteristics included a lower rate of minimally invasive surgery, a higher proportion of total pelvic exenterations, and longer postoperative ...
Nobuaki Hoshino +5 more
wiley +1 more source

