Results 21 to 30 of about 185,055 (265)

Current status and future investment potential in renewable energy in Jordan: An overview

open access: yesHeliyon, 2020
Jordan imports 94% of its oil and gas (fossil fuels) to meet its energy needs, leaving it vulnerable to variations in fuel price. Jordan's demand for energy is growing at a rate of 3% annually. In response, the government set a target of obtaining 10% of
Ghaida Abu-Rumman   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Supply Considerations for Scaling Up Clean Cooking Fuels for Household Energy in Low‐ and Middle‐Income Countries

open access: yesGeoHealth, 2019
Promoting access to clean household cooking energy is an important subject for policy making in low‐ and middle‐income countries, in light of urgent and global efforts to achieve universal energy access by 2030 (Sustainable Development Goal 7).
E. Puzzolo   +7 more
doaj   +1 more source

Towards achieving sustainable development Goal 7 (Affordable and Clean Energy) through a transition to decentralised energy systems in South Africa

open access: yesInternational Journal of Research in Business and Social Science (2147- 4478), 2023
In a decentralised system, energy-producing facilities are located closer to the location of energy consumption. A Decentralized Energy system decreases the need for fossil fuels, boosts eco-efficiency, and enables the best possible use of renewable energy sources and combined heat and power.
Shingirai Mugambiwa   +1 more
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Access to sources of stable, sustainable, and modern energy as a goal of sustainable development in the European Union: Are the Scandinavian countries leading the energy transition?

open access: yesEntrepreneurial Business and Economics Review
Objective: The objective of the article is to classify European Union (EU) member states according to similarity in the area of sustainable development goal 7 (SDG7) of the United Nations (UN) Agenda 2030 on affordable and clean energy ...
Krzysztof Adam Firlej   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Contributions of artificial intelligence and digitization in achieving clean and affordable energy

open access: yesIntelligent Systems with Applications
Concerned by the continuous decline in the quality of life, poverty, environmental degradation, and escalated war and conflicts, the United Nations in 2015 instituted the 17 Sustainable Development Goals (SDGs) and 169 targets.
Omojola Awogbemi   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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