Results 31 to 40 of about 1,377,376 (300)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Access to sources of stable, sustainable, and modern energy as a goal of sustainable development in the European Union: Are the Scandinavian countries leading the energy transition?

Entrepreneurial Business and Economics Review
Objective: The objective of the article is to classify European Union (EU) member states according to similarity in the area of sustainable development goal 7 (SDG7) of the United Nations (UN) Agenda 2030 on affordable and clean energy ...
Krzysztof Adam Firlej, Chrystian Firlej, Lidia Luty   +2 more
doaj   +1 more source

Supply Considerations for Scaling Up Clean Cooking Fuels for Household Energy in Low‐ and Middle‐Income Countries

GeoHealth, 2019
Promoting access to clean household cooking energy is an important subject for policy making in low‐ and middle‐income countries, in light of urgent and global efforts to achieve universal energy access by 2030 (Sustainable Development Goal 7).
E. Puzzolo, H. Zerriffi, E. Carter, H. Clemens, H. Stokes, P. Jagger, J. Rosenthal, H. Petach   +7 more
doaj   +1 more source

Magnetic breakdown in a normal-metal - superconductor proximity sandwich

, 1997
We study the magnetic response of a clean normal-metal slab of finite thickness in proximity with a bulk superconductor. We determine its free energy and identify two (meta-)stable states, a diamagnetic one where the applied field is effectively screened,
A.C. Mota, A.C. Mota, A.C. Mota, A.D. Zaikin, A.L. Shelankov, Alban L. Fauchère, G. Eilenberger, Gianni Blatter, K.D. Usadel, P. Visani, S. Higashitani, Th. Bergmann, W. Belzig, Y. Oda   +13 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Contributions of artificial intelligence and digitization in achieving clean and affordable energy

Intelligent Systems with Applications
Concerned by the continuous decline in the quality of life, poverty, environmental degradation, and escalated war and conflicts, the United Nations in 2015 instituted the 17 Sustainable Development Goals (SDGs) and 169 targets.
Omojola Awogbemi, Daramy Vandi Von Kallon, K. Sunil Kumar   +2 more
doaj   +1 more source

Current status and future investment potential in renewable energy in Jordan: An overview

Heliyon, 2020
Jordan imports 94% of its oil and gas (fossil fuels) to meet its energy needs, leaving it vulnerable to variations in fuel price. Jordan's demand for energy is growing at a rate of 3% annually. In response, the government set a target of obtaining 10% of
Ghaida Abu-Rumman, Adnan I. Khdair, Sawsan I. Khdair   +2 more
doaj   +1 more source

Gluon saturation effects at forward rapidities at LHC in pp collisions

, 2009
We investigate hadrons and direct photon production in pp collisions at the LHC energy within the color-dipole approach. We show that greatest sensitivity to gluon saturation effects is reached at very forward rapidities in pp collisions at LHC (\sqrt{s}=
Rezaeian, Amir H.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source