Results 1 to 10 of about 1,220,691 (191)

Exosomal miRNA-720 as a potential diagnostic and prognostic biomarker for hepatocellular carcinoma [PDF]

The Korean Journal of Internal Medicine
Background/Aims Circulating exosomal microRNAs (miRNAs) can serve as diagnostic and prognostic biomarkers for cancer. This study aimed to identify specific miRNAs in serum exosomes of patients with hepatocellular carcinoma (HCC) and validate their ...
Ji Min Kim, Hye Seon Kim, Jin Seoub Kim, Ji Won Han, Soon Kyu Lee, Heechul Nam, Pil Soo Sung, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang   +10 more
doaj   +2 more sources

Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers

Pharmaceutics, 2021
Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expression ...
Hawon Yoo, Seul-Ki Choi, Jaeok Lee, So Hyeon Park, You Na Park, Soo-Yeon Hwang, Jae-Ho Shin, Younghwa Na, Youngjoo Kwon, Hwa Jeong Lee, Yun-Sil Lee   +10 more
doaj   +1 more source

In Vitro Cytotoxicity of Antiresorptive and Antiangiogenic Compounds on Oral Tissues Contributing to MRONJ: Systematic Review

Biomolecules, 2023
Background: Invasive dental treatment in patients exposed to antiresorptive and antiangiogenic drugs can cause medication-related osteonecrosis of the jaw (MRONJ). Currently, the exact pathogenesis of this disease is unclear.
Robert H. Guirguis, Leonard P. Tan, Rebecca M. Hicks, Aniqa Hasan, Tina D. Duong, Xia Hu, Jordan Y. S. Hng, Mohammad H. Hadi, Henry C. Owuama, Tamara Matthyssen, Michael McCullough, Federica Canfora, Rita Paolini, Antonio Celentano   +13 more
doaj   +1 more source

Milk-Derived Proteins and Peptides in Head and Neck Carcinoma Treatment

Biomolecules, 2022
Research investigating milk-derived proteins has brought to light the potential for their use as novel anticancer agents. This paper aims to systematically review studies examining the effectiveness of milk-derived proteins in the treatment of head and ...
Theresa Wang, Xinyi Liu, Yah Ying Ng, Kiera Tarleton, Amy Tran, Thomas Tran, Wen Yue Xue, Paul Youssef, Peiyu Yuan, Daniel Zhang, Rita Paolini, Antonio Celentano   +11 more
doaj   +1 more source

A Systematic Review of MicroRNA Signatures Associated with the Progression of Leukoplakia with and without Epithelial Dysplasia

Biomolecules, 2021
Oral cancer is a significant public health issue, being the eighth most common cancer worldwide with over 300,000 cases diagnosed annually. Early diagnosis and adequate management of oral potentially malignant disorders (OPMDs) before transformation into
Nadia Kaunein, Rishi Sanjay Ramani, Kendrick Koo, Caroline Moore, Antonio Celentano, Michael McCullough, Tami Yap   +6 more
doaj   +1 more source

The Role of Glucose Transporters in Oral Squamous Cell Carcinoma

Biomolecules, 2021
Oral squamous cell carcinoma (OSCC) is a prevalent malignancy associated with a poor prognosis. The Warburg effect can be observed in OSCCs, with tumours requiring a robust glucose supply.
Heinrich Botha, Camile S. Farah, Kendrick Koo, Nicola Cirillo, Michael McCullough, Rita Paolini, Antonio Celentano   +6 more
doaj   +1 more source

Commonly Prescribed Anticoagulants Exert Anticancer Effects in Oral Squamous Cell Carcinoma Cells In Vitro

Biology, 2022
Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer. With anticoagulant usage on the rise, it is important to elucidate their potential effects on tumour biology and interactions with chemotherapeutics.
Li-Qiao R. Ling, Zichen Lin, Rita Paolini, Camile S. Farah, Michael McCullough, Mathew A. W. T. Lim, Antonio Celentano   +6 more
doaj   +1 more source

Comparative assessment of the survival, stability and occlusal settling between two types of thermoplastic retainers: a prospective clinical trial

Australasian Orthodontic Journal, 2022
A controlled clinical trial was undertaken to compare the effectiveness of Vivera® and Duran® retainers with regard to the survival, stability and occlusal settling over the first 6 months of retention following the completion of clear aligner treatment.
Cunning Bethany, Sahhar Alison, Lawrence Sarah, Manton David, Schneider Paul   +4 more
doaj   +1 more source

Coracoid process transfer and distal clavicle resection for chronic acromioclavicular separation

JSES International, 2023
Background: Dewar’s procedure for transferring the coracoid process with the short head of biceps and coracobrachialis was reported in 1965 for treatment of both acute and chronic acromioclavicular (AC) joint separation, but little contemporary ...
Hiroaki Inui, MD, PhD, Shin Osawa, PhD, Kie Mimori, MD, PhD   +2 more
doaj   +1 more source

Changes in NMDA Receptor Function in Rapid Ischemic Tolerance: A Potential Role for Tri-Heteromeric NMDA Receptors

Biomolecules, 2022
In this study, we characterize biophysical changes in NMDA receptor function in response to brief non-injurious ischemic stress (ischemic preconditioning).
Mian Xie, Tiandong Leng, Samaneh Maysami, Andrea Pearson, Roger Simon, Zhi-Gang Xiong, Robert Meller   +6 more
doaj   +1 more source