Results 51 to 60 of about 2,170,720 (292)

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

From competition and conversion to co-operation and conversation: Dynamics of Christian-Muslim engagement [PDF]

, 2006
Two books, Islam & the West Post 9/11 and Islam and the West: reflections from Australia, cover a range of theoretical issues, regional-specific topics and case studies that explore issues related to the theme of Islam and the West.
Pratt, Douglas
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Evaluation of a composite pain scale including facial expressions for detecting orthopedic pain in lame dairy cows

Journal of Dairy Science
: Orthopedic disease, presenting as lameness, is a common cause of pain in dairy cattle, often implying a prolonged course of disease, with significant economic losses and impaired animal welfare.
Maja Söderlind, Katrina Ask, Anna Leclercq, Therése Åkesson, Jean-Francois Valarcher, Elin Hernlund, Pia Haubro Andersen, Marie Rhodin   +7 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Diagnostic and Prognostic Performance of Metabolic Signatures in Pancreatic Ductal Adenocarcinoma: The Clinical Application of Quantitative NextGen Mass Spectrometry

Metabolites
With 64,050 new diagnoses and 50,550 deaths in the US in 2023, pancreatic ductal adenocarcinoma (PDAC) is among the most lethal of all human malignancies. Early detection and improved prognostication remain critical unmet needs.
Paulo D’Amora, Ismael D. C. G. Silva, Steven S. Evans, Adam J. Nagourney, Katharine A. Kirby, Brett Herrmann, Daniela Cavalheiro, Federico R. Francisco, Paula J. Bernard, Robert A. Nagourney   +9 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Advanced Dual-Satellite Method for Detection of Low Stratus and Fog near Japan at Dawn from FY-4A and Himawari-8

Remote Sensing, 2021
The detection of low stratus and fog (LSF) at dawn remains limited because of their optical features and weak solar radiation. LSF could be better identified by simultaneous observations of two geostationary satellites from different viewing angles.
Jung-Hyun Yang, Jung-Moon Yoo, Yong-Sang Choi   +2 more
doaj   +1 more source

An O(750) GeV Resonance and Inflation

, 2016
We study the possibility of a heavy scalar or pseudoscalar in TeV-scale beyond the Standard Model scenarios being the inflaton of the early universe in light of the recent O(750) GeV diphoton excess at the LHC.
Hamada, Yuta, Noumi, Toshifumi, Shiu, Gary, Sun, Sichun   +3 more
core   +2 more sources

What is the gamma gamma resonance at 750 GeV? [PDF]

, 2015
Run 2 LHC data show hints of a new resonance in the diphoton distribution at an invariant mass of 750 GeV. We analyse the data in terms of a new boson, extracting information on its properties and exploring theoretical interpretations.
Franceschini, Roberto, Giudice, Gian F., Kamenik, Jernej F., McCullough, Matthew, Pomarol, Alex, Rattazzi, Riccardo, Redi, Michele, Riva, Francesco, Strumia, Alessandro, Torre, Riccardo   +9 more
core   +1 more source