Results 191 to 200 of about 793,486 (305)

Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies

open access: yesAdvanced Science, EarlyView.
This review article delves into the cutting‐edge advancements in gene editing technology, with a particular focus on prime editor proteins and their engineered variants. The authors provide a thorough examination of recent developments that have addressed key challenges in the field, including improved precision, enhanced editing efficiency, and ...
Abhijith Koodamvetty   +1 more
wiley   +1 more source

(780) [PDF]

open access: bronze, 2007
Richard L. Illgen   +4 more
openalex   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare   +7 more
wiley   +1 more source

Optical properties of gold nanoclusters constructed from Au13 units

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
This review summarizes various optical properties of gold nanoclusters that consist of Au13 motifs. The structural evolution from Au13 to Au25, Au37, and Au60 is illustrated with increasing number of the Au13 building blocks. The review on the photo‐physics of Au13 family provides a comprehensive understanding of Au13‐assembled nanoclusters, which is ...
Jie Kong   +3 more
wiley   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

open access: yesAdvanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He   +6 more
wiley   +1 more source

Charge generation in organic solar cells: Journey toward 20% power conversion efficiency

open access: yesAggregate, Volume 3, Issue 6, December 2022., 2022
Herein, a photophysicist's views on charge generation in organic solar cells is discussed. Recent steady‐state and time‐resolved spectroscopic studies regarding the exciton diffusion to donor:acceptor interfaces, charge transfer at the donor:acceptor interface, and long‐range spatial dissociation of charge transfer states are highlighted.
Yasunari Tamai
wiley   +1 more source

A Hf(IV)‐Coordinated NIR‐II Fluorescence “Turn‐On” Nanoprobe for Precise Imaging‐Guided Surgery in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Based on the FDA‐approved fluorescent dye ICG, a Hf(IV)‐coordinated NIR‐II fluorescence “turn‐on” nanoprobe is constructed. This ultrasensitive nanoprobe can effectively accumulate in tumor sites and recover the fluorescence of ICG specifically in tumor microenvironment, accurately identifying submillimeter‐sized tumors with high sensitivity for real ...
Yueyang He   +10 more
wiley   +1 more source

780 Video Presentation: Irving S. Cooper, MD (1922–1985)

open access: hybrid, 2001
Mark Hornyak   +2 more
openalex   +1 more source

780: Mid-trimester Nugent score and vaginal pH in overweight and obese women at risk for preterm birth [PDF]

open access: bronze, 2008
Dana Figueroa   +4 more
openalex   +1 more source

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