Results 31 to 40 of about 88,596 (285)

Deceleration of the E1P-E2P Transition and Ion Transport by Mutation of Potentially Salt Bridge-forming Residues Lys-791 and Glu-820 in Gastric H+/K+-ATPase*

Journal of Biological Chemistry, 2010
A lysine residue within the highly conserved center of the fifth transmembrane segment in PIIC-type ATPase α-subunits is uniquely found in H,K-ATPases instead of a serine in all Na,K-ATPase isoforms. Because previous studies suggested a prominent role of
Katharina L. Dürr, I. Seuffert, T. Friedrich   +2 more
semanticscholar   +1 more source

Doxycycline Enhances Survival and Self-Renewal of Human Pluripotent Stem Cells

Stem Cell Reports, 2014
We here report that doxycycline, an antibacterial agent, exerts dramatic effects on human embryonic stem and induced pluripotent stem cells (hESC/iPSCs) survival and self-renewal. The survival-promoting effect was also manifest in cultures of neural stem
Mi-Yoon Chang, Yong-Hee Rhee, Sang-Hoon Yi, Su-Jae Lee, Rae-Kwon Kim, Hyongbum Kim, Chang-Hwan Park, Sang-Hun Lee   +7 more
doaj   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, EarlyView.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

Updated Mass, Eccentricity, and Tidal Heating Constraints for the Earth-sized Planet LP 791-18 d

The Astronomical Journal
LP 791-18 d is a temperate Earth-sized planet ( R _P = 1.03 R _⊕ , P = 2.76 days) orbiting a late M dwarf, with an interior super-Earth (LP 791-18 b, R _P = 1.2 R _⊕ , P = 0.95 days) and an exterior sub-Neptune (LP 791-18 c, R _P = 2.5 R _⊕ , P = 4.99 ...
Michael Greklek-McKeon, Heather A. Knutson, W. Garrett Levine, Renyu Hu, Morgan Saidel, Jonathan Gomez Barrientos, Konstantin Batygin, Björn Benneke   +7 more
doaj   +1 more source

Chiral Molecular Configuration‐Mediated Crystallization of Perovskites for High‐Performance Solar Cells

Advanced Energy Materials, EarlyView.
In this work, we propose a chiral stereo‐anchoring strategy to modulate the colloidal evolution and crystallization behavior of FAPbI3 perovskites via stereochemical molecular design, which effectively regulates nucleation kinetics and promotes ordered crystal growth.
Runkang Wang, Yujie Zhu, Jiaxue You, Yunfan Wang, Jiarong Wu, Jinghao Ge, Pengda Tong, Shilong Jia, Xiaogang Wang, Yiran Tao, Hao‐Chung Kuo, Adel Najar, Lu Zhang, Yuanhao Gong, Shengzhong (Frank) Liu   +14 more
wiley   +1 more source

A brain-computer interface that evokes tactile sensations improves robotic arm control

Science, 2021
A boost for brain–computer interfaces The finely controlled movement of our limbs requires two-way neuronal communication between the brain and the body periphery.
Sharlene N. Flesher, J. Downey, Jeffrey M. Weiss, Christopher L. Hughes, Angelica J. Herrera, E. Tyler-Kabara, M. Boninger, J. Collinger, R. Gaunt   +8 more
semanticscholar   +1 more source

Do Sojourn Effects on Personality Trait Changes Last? A Five‐Year Longitudinal Study

European Journal of Personality, EarlyView., 2020
Abstract This study examined sojourners' long‐term personality trait changes over five years, extending previous research on immediate sojourn effects. A sample of German students (N = 1095) was surveyed thrice (T1–T3) over the course of an academic year.
Julia Richter, Julia Zimmermann, Franz J. Neyer, Christian Kandler, Mitja Back   +4 more
wiley   +1 more source

Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis

Scientific Reports
Multiple sclerosis (MS) is a chronic neurological disease characterized by inflammatory demyelination that disrupts neuronal transmission resulting in neurodegeneration progressive disability.
Michael M. Poon, Kym I. Lorrain, Karin J. Stebbins, Geraldine C. Edu, Alexander R. Broadhead, Ariana O. Lorenzana, Bryanna E. Paulson, Christopher S. Baccei, Jeffrey R. Roppe, Thomas O. Schrader, Lino J. Valdez, Yifeng Xiong, Austin C. Chen, Daniel S. Lorrain   +13 more
doaj   +1 more source

Nonocclusive Mesenteric Ischemia Rescued by Immediate Surgical Exploration in a Boy with Severe Neurodevelopmental Disability

Case Reports in Pediatrics, 2019
Background. Nonocclusive mesenteric ischemia (NOMI) defines acute mesenteric ischemia without occlusion of the mesenteric arteries. The most common cause of NOMI is vasoconstriction or vasospasm of a mesenteric artery. NOMI generally affects patients >50 
Manami Mizumoto, Fumihiro Ochi, Toshihiro Jogamoto, Kentaro Okamoto, Mitsumasa Fukuda, Toshifumi Yamauchi, Toyohisa Miyata, Ryo Tashiro, Mariko Eguchi, Riko Kitazawa, Eiichi Ishii   +10 more
doaj   +1 more source

Nontobacco Nicotine Dependence Is Associated With Perioperative Complications and Repeat Surgery After Arthroscopic Rotator Cuff Repair

Arthroscopy, EarlyView.
Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino, Alexander N. Berk, Logan M. Good, Jeremy M. Adelstein, Robert J. Wetzel, George Ochenjele, Joshua K. Napora   +6 more
wiley   +1 more source