Results 41 to 50 of about 4,470,378 (285)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Clinical validation of the Hilab lens for AI supported point of care CBC testing in pediatric oncology

open access: yesCommunications Medicine
Background Complete blood count (CBC) testing is critical for diagnosing and monitoring hematological conditions, including leukemia. However, conventional analyzers require specialized infrastructure and trained personnel, limiting access in resource ...
Aléxia Thamara Gasparin   +13 more
doaj   +1 more source

Éticas falibles para máquinas (in)falibles

open access: yesArbor: Ciencia, Pensamiento y Cultura, 2021
Los códigos éticos humanos no son coherentes en su diseño ni tampoco tienen una distribución universal. Por lo tanto, la imposible universalidad ni completitud de los sistemas éticos para la inteligencia artificial (IA) es algo evidente que tan sólo fue ...
Jordi Vallverdú, Sarah Boix
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

جداسازی و شناسایی مولکولی و الگوی حساسیت آنتی‌بیوتیک رودوکوکوس‌های جدا شده از بیماران مبتلا به سرطان در شیراز [PDF]

open access: yesمجله دانشکده پزشکی اصفهان
مقاله پژوهشی مقدمه: شیوع عفونت‌های فرصت‌طلب، مانند عفونت‌های ناشی از گونه‌های رودوکوکوس، یک مسأله‌ی مهم در افراد دارای نقص ایمنی، به‌ویژه بیماران مبتلا سرطان است.
راضیه هلالی پرگالی   +2 more
doaj   +1 more source

Assessment of livelihood wellbeing and empowerment of hill women through Farmers Producer Organization: A case of women based Producer Company in Uttarakhand

open access: yesThe Indian Journal of Agricultural Sciences, 2020
Hill agriculture is different from agriculture at plains, in respect to land type, altitude and climate, in addition to lack of infrastructure and fragmented land holding.
Anirban mukherjee   +6 more
doaj   +1 more source

Evaluation of the whanau carers training programme delivered by LIFE Unlimited [PDF]

open access: yes, 2004
In response to the needs of Maori informal carers, a training programme was developed for whanau carers in the Waikato region. It was delivered by LIFE Unlimited.
Ashwell, Allanah   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Genetic Relationship of Productive Life, Production and Type Traits of Korean Holsteins at Early Lactations [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2015
The present study was performed to study the genetic relationship of productive life with production and type traits of Korean Holsteins at first three lactations.
Nidarshani Wasana   +7 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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