Results 141 to 150 of about 985,419 (304)

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Hydrogen Gas Therapy in Schizophrenia: Potential Neuroprotective Effects From an Animal Study. [PDF]

Neuropsychopharmacol Rep
Miyake N, Haga T, Hirano SI, Ichikawa Y, Oguchi Y, Ando K.   +5 more
europepmc   +1 more source

TESLA Technical Design Report Part III: Physics at an e+e- Linear Collider

, 2001
The TESLA Technical Design Report Part III: Physics at an e+e- Linear ColliderComment: 192 pages, 131 figures. Some figures have reduced quality. Full quality figures can be obtained from http://tesla.desy.de/tdr. Editors - R.-D. Heuer, D.J.
Aguilar-Saavedra, J. A., Alcaraz, J., Ali, A., Ambrosanio, S., Andreazza, A., Andruszkow, J., Badelek, B., Ballestrero, A., Barklow, T., Bartl, A., Battaglia, M., Behnke, T., Belanger, G., Benson, D., Berggren, M., Bernreuther, W., Besancon, M., Biebel, J., Biebel, O., Bigi, I., Binoth, T., Blair, G. A., Blochinger, C., Blumlein, J., Boonekamp, M., Boos, E., Borissov, G., Brandenburg, A., Brient, J. -C., Bruni, G., Burrows, P., Busser, K., Casalbuoni, R., Castanier, C., Chankowski, P., Chekanov, A., Chierici, R., Choi, S. Y., Christova, P., Ciafaloni, P., Comelli, D., Conteras, G., Da Silva, W., Danilov, M., de Boer, W., De Curtis, S., de Freitas, P. Mora, De Jong, S. J., De Roeck, A., De Wolf, E., Deandrea, A., Denner, A., Desch, K., Dittmaier, S., Djordjadze, V., Djouadi, A., Dominici, D., Doncheski, M., Dova, M. T., Drollinger, V., Eberl, H., Erler, J., Eskreys, A., Espinosa, J. R., Evanson, N., Fernandez, E., Forshaw, J., Fraas, H., Franke, F., Freitas, A., Gangemi, F., Garcia-Abia, P., Gatto, R., Gay, P., Gehrmann, T., Gensch, U., Ghodbane, N., Ginzburg, I. F., Godbole, R., Godfrey, S., Gounaris, G., Grazzini, M., Gross, E., Grzadkowski, B., Guasch, J., Gunion, J. F., Hagiwara, K., Han, T., Harder, K., Harlander, R., Hawkings, R., Heinemeyer, S., Hesselbach, S., Heuer, R. -D., Heusch, C. A., Hewett, J., Hiller, G., Hoang, A., Hollik, W., Illana, J. I., Ilyin, V. A., Indumathi, D., Ishihara, S., Jack, M., Jadach, S., Jankowski, P., Jegerlehner, F., Jezabek, M., Jikia, G., Jonsson, L., Jurkiewicz, P., Juste, A., Kagan, A., Kalinowski, J., Kalmykov, M., Kalyniak, P., Kamal, B., Kamoshita, J., Kanemura, S., Kapusta, F., Katsanevas, S., Keranen, R., Khoze, V., Kiiskinen, A., Kilian, W., Klasen, M., Kneur, J. L., Kniehl, B. A., Kobel, M., Kolodziej, K., Kramer, M., Kraml, S., Krawczyk, M., Kuhn, J. H., Kwiecinski, J., Laurelli, P., Leike, A., Letts, J., Lohmann, W., Lola, S., Lutz, P., Majerotto, W., Mannel, T., Martinez, M., Martyn, H. -U., Mattig, P., Mayer, T., Mele, B., Melles, M., Menges, W., Merino, G., Meyer, N., Miller, D. J., Miller, D. J., Minkowski, P., Miquel, R., Monig, K., Montagna, G., Moortgat-Pick, G., Moreau, G., Moretti, M., Moretti, S., Motyka, L., Moultaka, G., Muhlleitner, M., Nauenberg, U., Nisius, R., Nowak, H., Ohl, T., Orava, R., Orloff, J., Osland, P., Pancheri, G., Pankov, A. A., Papadopoulos, C., Paver, N., Peralta, D., Phillips, H. T., Picinini, F., Placzek, W., Pohl, M., Porod, W., Pukhov, A., Raspereza, A., Reid, D., Richard, F., Ridder, A. Gehrmann-De, Riemann, S., Riemann, T., Rosati, S., Roth, M., Roth, S., Royon, C., Ruckl, R., Ruiz-Morales, E., Sachwitz, M., Schieck, J., Schreiber, H. -J., Schulte, D., Schumacher, M., Settles, R. D., Seymour, M., Shanidze, R., Sjostrand, T., Skrzypek, M., Soldner-Rembold, S., Sopczak, A., Spiesberger, H., Spira, M., Steiner, H., Stratmann, M., Sumino, Y., Tapprogge, S., Telnov, V., Teubner, T., Tonazzo, A., Troncon, C., van der Bij, J. J., Veretin, O., Verzegnassi, C., Vest, A., Vicini, A., Videau, H., Vogelsang, W., Vogt, A., Vogt, H., Wackeroth, D., Wagner, A., Wallon, S., Weiglein, G., Weinzierl, S., Wengler, T., Wermes, N., Werthenbach, A., Wilson, G., Winter, M., Zarnecki, A. F., Zerwas, P. M., Ziaja, B., Zochowski, J.   +239 more
core  

Single‐Breathhold 3D MR Elastography in the Liver, With Simultaneous R2* and PDFF Mapping

Magnetic Resonance in Medicine, EarlyView.
Purpose To develop a sequence for the rapid acquisition of MR elastography (MRE) parameters in 3D, with simultaneous measurement of proton‐density fat fraction (PDFF) and R2* for multiparametric assessment of liver disease. Methods The proposed sequence uses an interleaved motion‐encoding scheme to acquire 3D volumes of all motion encodings and wave ...
Donovan P Tripp, Anne‐Sophie van Schelt, Omar Darwish, Karl P Kunze, Shamsa Al Harthy, Nader S Metwalli, Ahmed M Gharib, Claudia Prieto, René M Botnar, Ralph Sinkus, Radhouene Neji   +10 more
wiley   +1 more source

Intranasal delivery of the NMDA receptor antagonist MK-801 attenuates ultra-acute excitotoxic neurochemical responses after concussion in rats: comparative pharmacological evaluation against ketamine. [PDF]

Front Pharmacol
Masse I, Moquin L, Bouchard C, Legroux L, Gratton A, De Beaumont L.   +5 more
europepmc   +1 more source

Detecting social‐ecological fit in Natura 2000 governance and management: Evidence from LIFE projects focused on forest protected habitat types

People and Nature, EarlyView.
Abstract Protected areas represent complex social‐ecological systems that require governance and management approaches that valorise and enhance positive relationships between people and nature. This study analyses the alignment between social and ecological systems to detect the social‐ecological fit of projects focused on biodiversity conservation ...
Elena Andriollo, Elena Pisani, Mauro Masiero, Tommaso Sitzia, Thomas Campagnaro   +4 more
wiley   +1 more source

Precise regulation of missing linkers in MOF pervaporation membranes for desalination of hypersaline waters. [PDF]

Nat Commun
Dong Y, De Finnda C, Fu M, Zheng X, Lyu Q, Zhao M, Wang H, Yu HQ, Elimelech M.   +8 more
europepmc   +1 more source

Biodiversity science is improved when silent herbaria speak

PLANTS, PEOPLE, PLANET, EarlyView.
Herbaria in the Global South are critical yet underutilized resources for biodiversity science and often absent from international databases and research networks. We highlight the phenomenon of “silent herbaria” using Nigeria as a case study and quantify how these collections fill important gaps in global biodiversity knowledge.
Daniel A. Zhigila, Ryan J. Schmidt‐Knapik, Barbara M. Thiers, Suleiman D. Abdul, Salihu Abdullahi, Abdullahi A. AbdulRahaman, Emmanuel I. Aigbokhan, Gabriel A. Ajibade, Linus B. Ajikah, Ferdinand A. Akomaye, Abiodun E. Ayodele, Joseph J. Azila, Aliyu Babale, Abubakar Bello, Deborah M. Chukwuma, Emmanuel C. Chukwuma, Abubakar M. Dadile, Chimezie Ekeke, Iroka C. Finian, Abayomi E. Folorunso, Akanni T. Gbenga, Mohammed R. Haruna, Jemilat A. Ibrahim, Opeyemi S. Kolawole, Abubakar M. Liman, Ferdinand N. Mbagwu, Sunusi Namadi, Victor S. Njom, George I. Nodza, Felix I. Nwafor, Onyebuchi E. Nwankwo, Caleb D. Obadiah, Bamigboye S. Oloruntoba, Fatima B. J. Sawa, Yohanna C. Tumba, Musa Umar, Elizabeth N. Usen, Maryam M. Wabili, Charles C. Davis   +38 more
wiley   +1 more source

Impulsivity in NrCAM KO Mice Is Reduced by NMDAR Antagonist MK-801 but Not by AMPAR Antagonist CNQX. [PDF]

NeuroSci
Buhusi M, Buhusi CV.
europepmc   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source