Results 21 to 30 of about 136,094 (264)

A Two-Stage Estimation Approach to Cox Regression Under the Five-Parameter Spline Model

open access: yesMathematics
The Cox proportional hazards model is one of the most popular regression models for censored survival data. In the Cox model, the baseline hazard function is often modeled by cubic spline functions.
Ren Teranishi   +2 more
doaj   +1 more source

Antihypertensive effect of piperitenone oxide on spontaneously hypertensive rat by regulating calcium balance and reducing endothelin-1 secretion

open access: yesBangladesh Journal of Pharmacology, 2017
The purpose of this study was to investigate the antihypertensive mecha-nisms of piperitenone oxide in spontaneously hypertensive rat (SHR). Compared to control SHR, piperitenone oxide reduced the systolic blood pressure and serum endothelium-1 (ET-1 ...
Wei Lan   +5 more
doaj   +1 more source

Biological Analyses-Derived Translational Findings in the T Cell Receptor Alpha Chain Knockout Mouse as an Experimental Model for Ulcerative Colitis

open access: yesInternational Journal of Translational Medicine, 2021
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that affects many individuals throughout their lives. Ulcerative colitis (UC) and Crohn’s disease (CD) are two major forms of IBD.
Emiko Mizoguchi   +2 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

Tortuous Common Carotid Artery: A Report of Four Cases Observed in Cadaveric Dissections

open access: yesCase Reports in Otolaryngology, 2016
A tortuous common carotid artery poses a high risk of injury during tracheotomy. Preoperative diagnosis is therefore important to avoid serious complications.
Joe Iwanaga   +4 more
doaj   +1 more source

Differential Item Functioning on the Patient Health Questionnaire 8 by Disease Subtype, Language, Sex, and Age Among People With Systemic Sclerosis: A Scleroderma Patient‐Centered Intervention Network Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Somatic items used in depression assessments can potentially overlap with symptoms related to physical illness, including systemic sclerosis (SSc). No studies have looked at whether somatic depression items may be influenced by diffuse versus limited SSc disease subtypes, which are associated with varying degrees of symptom presentation.
Sophie Hu   +110 more
wiley   +1 more source

Parametric Distributions for Survival and Reliability Analyses, a Review and Historical Sketch

open access: yesMathematics, 2022
During its 330 years of history, parametric distributions have been useful for survival and reliability analyses. In this paper, we comprehensively review the historical backgrounds and statistical properties of a number of parametric distributions used ...
Nanami Taketomi   +3 more
doaj   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Deposition of Nickel-tungsten-phosphorus Coatings on Pure Copper in a Saline Water Environment

open access: yesInternational Journal of Electrochemical Science, 2021
Corrosion of copper caused by chloride species restricts advances in the maritime industry. In the present study, ternary Ni-W-P alloys were electrodeposited on copper in DC current mode to improve the corrosion resistance of the matrix.
Pei-Jing Teng   +2 more
doaj   +1 more source

Creep Properties and Deformation Mechanism of Additively Manufactured NiAl‐CrMo Composites

open access: yesAdvanced Engineering Materials, EarlyView.
Additively manufactured NiAl‐CrMo composites contain numerous interfaces and cell boundaries that control their creep response. At 700°C under high applied stress, creep is dominated by dislocation‐controlled power‐law mechanisms. At 800°C–900°C and lower stresses, creep is primarily diffusion‐controlled along cell boundaries.
Jan Vollhüter   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy