Results 21 to 30 of about 180,078 (285)

Soluble Immune Checkpoint Molecules as Predictors of Efficacy in Immuno-Oncology Combination Therapy in Advanced Renal Cell Carcinoma

Current Oncology
Immuno-oncology (IO) combination therapy is the first-line treatment for advanced renal cell carcinoma (RCC). However, biomarkers for predicting the response to IO combination therapy are lacking.
Kosuke Ueda, Keiichiro Uemura, Naoki Ito, Yuya Sakai, Satoshi Ohnishi, Hiroki Suekane, Hirofumi Kurose, Tasuku Hiroshige, Katsuaki Chikui, Kiyoaki Nishihara, Makoto Nakiri, Shigetaka Suekane, Sachiko Ogasawara, Hirohisa Yano, Tsukasa Igawa   +14 more
doaj   +1 more source

Short-Term Association of Add-On Gosha-Jinki-Gan with Sleep and Nocturia Outcomes in Patients with Persistent Nocturia Despite Desmopressin: A Real-World Study

Medicina
Background and Objectives: Given the limited therapeutic options for patients with persistent nocturia despite desmopressin treatment, we aimed to evaluate the short-term effects of add-on Gosha-jinki-gan therapy on hours of undisturbed sleep (HUS) and ...
Hirofumi Kurose, Hiroshi Kishimoto, Keisuke Komiya, Kosuke Ueda, Katsuaki Chikui, Keiichiro Uemura, Kiyoaki Nishihara, Makoto Nakiri, Shigetaka Suekane, Tsukasa Igawa   +9 more
doaj   +1 more source

Adverse Audio-Vestibular Effects of Drugs and Vaccines Used in the Treatment and Prevention of COVID-19: A Review

Audiology Research, 2022
(1) Background: The purpose of this article is to review pharmacological treatments for COVID-19 (currently approved by the EMA (European Medical Agency) and FDA (Food and Drug Administration)) and highlight their potential audio-vestibular side-effects ...
Magdalena B. Skarzynska, Monika Matusiak, Piotr H. Skarzynski   +2 more
doaj   +1 more source

Computed Tomographic Epidurography in Patients with Low Back Pain and Leg Pain: A Single-Center Observational Study

Diagnostics, 2022
This study was conducted to analyze the findings and benefits of computed tomography (CT) epidurography in patients with low back and leg pain and compare these findings with those of magnetic resonance imaging (MRI) images.
Kimiaki Yokosuka, Kimiaki Sato, Kei Yamada, Tatsuhiro Yoshida, Takahiro Shimazaki, Shinji Morito, Kouta Nishida, Atsushi Matsuo, Takuma Fudo, Naoto Shiba   +9 more
doaj   +1 more source

A Two-Stage Estimation Approach to Cox Regression Under the Five-Parameter Spline Model

Mathematics
The Cox proportional hazards model is one of the most popular regression models for censored survival data. In the Cox model, the baseline hazard function is often modeled by cubic spline functions.
Ren Teranishi, Kyoji Furukawa, Takeshi Emura   +2 more
doaj   +1 more source

Antihypertensive effect of piperitenone oxide on spontaneously hypertensive rat by regulating calcium balance and reducing endothelin-1 secretion

Bangladesh Journal of Pharmacology, 2017
The purpose of this study was to investigate the antihypertensive mecha-nisms of piperitenone oxide in spontaneously hypertensive rat (SHR). Compared to control SHR, piperitenone oxide reduced the systolic blood pressure and serum endothelium-1 (ET-1 ...
Wei Lan, Hong Ping Zhang, Ying Wang, Min Jiang, Qian Li, Dongqing An   +5 more
doaj   +1 more source

Counterion Dependent Side‐Chain Relaxation Stiffens a Chemically Doped Thienothiophene Copolymer

Advanced Functional Materials, EarlyView.
Oxidation of a thienothiophene copolymer, p(g3TT‐T2), via different doping strategies and dopant molecules resulted in materials with similar oxidation levels and a high electrical conductivity of ≈100 S cm−1. However, mechanical properties varied significantly, with sub‐glass transition temperatures and elastic moduli spanning from –44°C to –3°C and ...
Mariavittoria Craighero, Meghna Jha, Elsa Veronica Flores‐Vela, Joost Kimpel, Andreas Schaefer, Jiali Guo, Jesika Asatryan, Alberto Peinador Veiga, Shuichi Haraguchi, Per‐Anders Carlsson, Jaime Martín, Mariano Campoy‐Quiles, Christian Müller   +12 more
wiley   +1 more source

Trykk 830 [PDF]

, 1963
830 med tittel: Ekspedisjonsbestemmelser for befordring av gods og levende dyr i norsk ...
Norges statsbaner
core  

Biological Analyses-Derived Translational Findings in the T Cell Receptor Alpha Chain Knockout Mouse as an Experimental Model for Ulcerative Colitis

International Journal of Translational Medicine, 2021
Inflammatory bowel disease (IBD) is a group of chronic inflammatory disorders that affects many individuals throughout their lives. Ulcerative colitis (UC) and Crohn’s disease (CD) are two major forms of IBD.
Emiko Mizoguchi, Takayuki Sadanaga, Toshiyuki Okada   +2 more
doaj   +1 more source

Photo‐Switchable Molecular Module Programming PET Biodegradation in Aquatic Environments

Advanced Functional Materials, EarlyView.
We address the plastic durability paradox by integrating an itaconic acid–derived pyrrolidone module into polymer backbones. Sunlight in water triggers Norrish Type I ring‐opening and hydrophilization, enabling rapid biodegradation into nontoxic minerals.
Mohammad Asif Ali, Jixin Zheng, Satoshi Wakai, Jie Liu, Hidetaka Nomaki, Misato Tsukatani, Noriyuki Isobe, Jingcheng Sang, Yuriko Aoki, Hideo Okamura, Daisuke Sasaki, Chiaki Ogino, Yuzo Yamazaki, Takashi Nishikaze, Kenji Takada, Maiko K. Okajima, Tatsuo Kaneko   +16 more
wiley   +1 more source