Results 11 to 20 of about 2,121,031 (203)
Hsp-90 and the biology of nematodes [PDF]
BACKGROUND: Hsp-90 from the free-living nematode Caenorhabditis elegans is unique in that it fails to bind to the specific Hsp-90 inhibitor, geldanamycin (GA).
Emes, R.D. +4 more
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New exact solution approaches for the split delivery vehicle routing problem
In this study, we propose exact solution methods for the split delivery vehicle routing problem (SDVRP). We first give a new vehicle-indexed flow formulation for the problem and then a relaxation obtained by aggregating the vehicle-indexed variables over
Gizem Ozbaygin, Oya Karasan, Hande Yaman
doaj +1 more source
Many practical combinatorial optimization problems can be described by integer linear programs having an exponential number of variables, and they are efficiently solved by column generation algorithms.
Christian Artigues +2 more
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An improved cut-and-solve algorithm for the single-source capacitated facility location problem
In this paper, we present an improved cut-and-solve algorithm for the single-source capacitated facility location problem. The algorithm consists of three phases.
SuneLauth Gadegaard +2 more
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Bilevel programming for price-based electricity auctions: a revenue-constrained case
This paper describes the application of bilevel programming to a class of real-life problems in the field of electric power systems. Within the context of electricity markets, market-clearing procedures, i.e., auction models, are used by an independent ...
Ricardo Fernández-Blanco +2 more
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In the two-dimensional guillotine cutting-stock problem, the objective is to minimize the number of large plates used to cut a list of small rectangles.
François Clautiaux +3 more
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Complementarity-based nonlinear programming techniques for optimal mixing in gas networks
We consider nonlinear and nonsmooth mixing aspects in gas transport optimization problems. As mixed-integer reformulations of pooling-type mixing models already render small-size instances computationally intractable, we investigate the applicability of ...
FalkM. Hante, Martin Schmidt
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A series of new pyrazolo[4,3-e][1,2,4]triazine acyclonucleosides 2−5 and 8 were prepared and evaluated for their anticancer activity against human cancer cell lines (MCF-7, K-562) and CDK2/E, as well as Abl protein kinases inhibitors. Lipophilicity
Mariusz Mojzych +4 more
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A complete search method for the relaxed traveling tournament problem
The traveling tournament problem is a sports scheduling problem that includes two major issues in creating timetables: home/away pattern feasibility and travel distance.
Filipe Brandão, JoãoPedro Pedroso
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