Results 31 to 40 of about 382,119 (141)

Comparison of Current Complex Variable Boundary Element Method (CVBEM) Capabilities in Basis Functions, Node Positioning Algorithms (NPAs), and Coefficient Determination Methods

International Journal of Computational Methods & Experimental Measurements, 2023
CVBEM is a numerical method of solving boundary value problems that satisfy Laplace's Equation in two dimensions. Three key parameters that impact the computational error and functionality of CVBEM are the basis function, the positions of the modeling ...
S. Ali, Theodore V. Hromadka
semanticscholar   +1 more source

Interpreting missense variants: comparing computational methods in human disease genes CDKN2A, MLH1, MSH2, MECP2, and tyrosinase (TYR)

Human Mutation, 2007
The human genome contains frequent single‐basepair variants that may or may not cause genetic disease. To characterize benign vs. pathogenic missense variants, numerous computational algorithms have been developed based on comparative sequence and/or ...
Philip Chan, Sekhar Duraisamy, P. Miller, Joan A. Newell, Caroline McBride, J. Bond, T. Raevaara, Saara Ollila, Minna Nyström, Andrew J. Grimm, J. Christodoulou, W. Oetting, M. Greenblatt   +12 more
semanticscholar   +1 more source

A space-time pseudospectral discretization method for solving diffusion optimal control problems with two-sided fractional derivatives

, 2018
We propose a direct numerical method for the solution of an optimal control problem governed by a two-side space-fractional diffusion equation. The presented method contains two main steps.
Ali, Mushtaq Salh, Bozorgnia, Farid, Khosravian-Arab, Hassan, Shamsi, Mostafa, Torres, Delfim F. M.   +4 more
core   +1 more source

Advancing Drug Safety in Drug Development: Bridging Computational Predictions for Enhanced Toxicity Prediction

Chemical Research in Toxicology
The attrition rate of drugs in clinical trials is generally quite high, with estimates suggesting that approximately 90% of drugs fail to make it through the process.
Ana M B Amorim, L. F. Piochi, A. T. Gaspar, A. J. Preto, N. Rosário‐Ferreira, I. Moreira   +5 more
semanticscholar   +1 more source

Opposition based Ensemble Micro Differential Evolution

, 2017
Differential evolution (DE) algorithm with a small population size is called Micro-DE (MDE). A small population size decreases the computational complexity but also reduces the exploration ability of DE by limiting the population diversity. In this paper,
Rahnamayan, Shahryar, Salehinejad, Hojjat, Tizhoosh, Hamid R.   +2 more
core   +1 more source

Comparison of computational methods for identifying translation initiation sites in EST data

BMC Bioinformatics, 2004
BackgroundExpressed Sequence Tag (EST) sequences are generally single-strand, single-pass sequences, only 200–600 nucleotides long, contain errors resulting in frame shifts, and represent different parts of their parent cDNA.
Afshin Nadershahi, S. Fahrenkrug, L. Ellis   +2 more
semanticscholar   +1 more source

Evaluating syntax-driven approaches to phrase extraction for MT [PDF]

, 2009
In this paper, we examine a number of different phrase segmentation approaches for Machine Translation and how they perform when used to supplement the translation model of a phrase-based SMT system. This work represents a summary of a number of years of
Groves, Declan, Penkale, Sergio, Srivastava, Ankit Kumar, Tinsley, John   +3 more
core  

Spatially Averaged Epithelial/Absorbed Power Density for Nonplanar Skin Models Exposed to Antenna at 10–90 GHz

IEEE Access
International guidelines and standards for human protection from electromagnetic fields have been revised recently. The epithelial/absorbed power density (APD) has been used as a new physical quantity for local exposure to frequencies > 6 GHz, related to
Kun Li, S. Kodera, D. Poljak, Y. Diao, K. Sasaki, Shuai Zhang, Ming Yao, A. Kapetanović, Congsheng Li, Tongning Wu, T. Liebig, Winfried Simon, Akimasa Hirata   +12 more
semanticscholar   +1 more source

Neoadjuvant chemotherapy followed by chemoradiation and surgery with and without cetuximab in patients with resectable esophageal cancer: a randomized, open-label, phase III trial (SAKK 75/08)

Annals of Oncology, 2018
Background This open-label, phase III trial compared chemoradiation followed by surgery with or without neoadjuvant and adjuvant cetuximab in patients with resectable esophageal carcinoma. Patients and methods Patients were randomly assigned (1 : 1) to
T. Ruhstaller, P. Thuss-Patience, S. Hayoz, Sabina Schacher, J. R. Knorrenschild, A. Schnider, L. Plasswilm, W. Budach, Wolfgang Eisterer, H. Hawle, C. Mariette, V. Hess, W. Mingrone, M. Montemurro, M. Girschikofsky, S. Schmidt, M. Bitzer, L. Bedenne, P. Brauchli, Michael Stahl   +19 more
semanticscholar   +1 more source

Optimization-Based Peptide Mass Fingerprinting for Protein Mixture Identification [PDF]

, 2008
*Motivation:* In current proteome research, peptide sequencing is probably the most widely used method for protein mixture identification. However, this peptide-centric method has its own disadvantages such as the immense volume of tandem Mass ...
Can Yang, Chao Yang, Jason Po-Ming Tam, Robert Z Qi, Weichuan Yu, Zengyou He   +5 more
core   +1 more source