Results 81 to 90 of about 118,223 (242)

PPAR-α Insufficiency Enhances Doxorubicin-Induced Nephropathy in PPAR-α Knockout Mice and a Murine Podocyte Cell Line

Cells
Peroxisome proliferator-activated receptor-alpha (PPAR-α) and its exogenous activators (fibrates) promote autophagy. However, whether the deleterious effects of PPAR-α deficiency on doxorubicin (DOX)-induced podocytopathy are associated with reduced ...
Kohei Matsuta, Kazuko Kamiyama, Toru Imamoto, Izumi Takeda, Shinya Masunaga, Mamiko Kobayashi, Naoki Takahashi, Kenji Kasuno, Masanori Hara, Masayuki Iwano, Tadashi Toyama, Hideki Kimura   +11 more
doaj   +1 more source

The female journey following sexual assault: Medical care, law enforcement and judicial outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Sexual violence affects 22% of Australian women, posing health and justice challenges. Systemic failures, fragmented data, and low conviction rates hinder effective responses. This study integrates Australian Capital Territory (ACT) medical and policing datasets to examine victim characteristics and case progression from clinical ...
Vanita Parekh, Michael Woodburn, Stephanie Leonard, Bridget Bourke, Janine McMinn, Anna Brkic, Ash Byron, Katelyn Pomroy   +7 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Hyperperfusion Improvement: A Potential Therapeutic Marker in Neuromyelitis Optica Spectrum Disorder (NMOSD)

Diagnostics
A 70-year-old Japanese woman with longstanding hearing loss and asthma developed floating sensations, left finger numbness, and postural instability one day after influenza vaccination, leading to hospital admission.
Koichi Kimura, Koji Hayashi, Mamiko Sato, Yuka Nakaya, Asuka Suzuki, Naoko Takaku, Hiromi Hayashi, Kouji Hayashi, Toyoaki Miura, Yasutaka Kobayashi   +9 more
doaj   +1 more source

Overcoming spectral limits of perovskite photodetectors for the infrared region

InfoScience, EarlyView.
Infrared (IR) photodetectors are vital for modern optoelectronics, but traditional inorganic semiconductors face limitations in cost, processing, and bandgap tunability. This review provides a summary of advanced strategies to extend metal halide perovskites into the IR region, categorizing approaches into intrinsic material engineering, physical ...
Jiean Li, Bobo Li, Mingxia Qiu, Wang Zhang, Xuan Fang   +4 more
wiley   +1 more source

Elderly drivers with pedal errors during emergency braking do not lift their leg

Transportation Research Interdisciplinary Perspectives
Pedal errors among elderly drivers may be more closely associated with a decline in motor control rather than cognitive function. However, the impact of motor control across all major joints in the lower limb, including the hip, knee, and ankle joints ...
Kazuki Fujita, Yasutaka Kobayashi, Koji Hayashi, Kaori Kawabata, Tomoki Ogawa, Hideaki Hori, Mamiko Sato, Masahito Hitosugi   +7 more
doaj   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Intraocular Pressure-Lowering Effect of Intraocular Lens Refixation in Patients with Elevated Intraocular Pressure Due to Intraocular Lens Subluxation

Medicina
Background and Objectives: To evaluate the surgical outcomes of intraocular lens (IOL) refixation with vitrectomy in patients with elevated intraocular pressure (IOP) due to IOL subluxation.
Kentaro Iwasaki, Ryohei Komori, Shogo Arimura, Yoshihiro Takamura, Masaru Inatani   +4 more
doaj   +1 more source

Inter‐Group Agreement in Chest Radiographic Quality Assessment: Comparing Final‐Year Students and Experienced Radiographers Across Three Quality Assessment Domains During the COVID‐19 Pandemic

Journal of Medical Radiation Sciences, EarlyView.
Final‐year radiography students and experienced radiographers assessed 70 chest radiographs using structured criteria for positioning, sharpness and anatomical visibility. The level of agreement was good to excellent across all three domains, with an overall ICC of 0.90.
Peter O'Reilly, Dania Abu Awwad, Ernest Ekpo, Warren Reed   +3 more
wiley   +1 more source

Paediatric computed tomography diagnostic reference levels in Africa: A systematic review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 139-147, March 2025.
Improvements in computed tomography (CT) technology have increased its applications in medical imaging. Variations in the paediatric DRLs indicate that harmonisation and standardisation of paediatric CT protocols are essential for the optimisation of paediatric doses. Abstract Introduction Improvements in computed tomography (CT) technology in terms of
Emmanuel Gyan, Christiana Subaar, George Edusei, Linda Antwi Nyarko   +3 more
wiley   +1 more source