Results 91 to 100 of about 11,372,062 (345)

The Thermodynamics of Quantum Systems and Generalizations of Zamolodchikov's C-theorem

open access: yes, 1993
In this paper we examine the behavior in temperature of the free energy on quantum systems in an arbitrary number of dimensions. We define from the free energy a function $C$ of the coupling constants and the temperature, which in the regimes where ...
A.H. Castro Neto   +21 more
core   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1471-1492, May 2025.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

First records of the Indo-Pacific Finless Porpoise Neophocaena phocaenoides (G. Cuvier, 1829) (Cetartiodactyla: Phocoenidae) from Sri Lanka

open access: yesJournal of Threatened Taxa, 2017
Thirty species of marine mammals have been recorded from Sri Lanka.  Amongst them the Indo-Pacific Finless Porpoise Neophocaena phocaenoides is the only representative of the family Phocoenidae.
Ranil P. Nanayakkara   +2 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Practical challenges in data‐driven interpolation: Dealing with noise, enforcing stability, and computing realizations

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView., 2023
Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley   +1 more source

Study of transmission pattern of COVID-19 among cardiac and noncardiac population using a nonlinear mathematical model

open access: yesComputational and Mathematical Biophysics
Recent studies have intensified the risk of post-COVID-19 cardiovascular diseases. In an effort to understand the intricate dynamics of COVID-19 infection, this article suggests a four-compartment model to portray the dynamic interplay between the ...
Shirisha Gopishetty, Vernekar Saroj
doaj   +1 more source

Age and gender differences in objectively measured physical activity in youth.

open access: yesMedicine & Science in Sports & Exercise, 2002
PURPOSE The purpose of this study was to evaluate age and gender differences in objectively measured physical activity (PA) in a population-based sample of students in grades 1-12.
S. Trost   +6 more
semanticscholar   +1 more source

Hydroblack 91 : report of the CTD Intercalibration Workshop [PDF]

open access: yes, 1992
An Intercalibration Workshop was held at the Woods Hole Oceanographic Institution (W.H.O.I.) from 1-10 December, 1991, for the CTD data acquired during HYDROBLACK '91. This intercalibration exercise was a prelude to an interdisciplinary HYDROBLACK '91
Aubrey, David G.   +6 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

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