Results 71 to 80 of about 91,208,433 (234)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Regularization Dependence of Quadratic Divergence Cancellations, VPI-IHEP-92/10
, 1992 Certain results related to the cancellation of quadratic divergences, which had been obtained using dimensional reduction, are reconsidered using a nonlocal regulator. The results obtained are shown to depend strongly on the regulator. Specifically, it is shown that a certain result of Al-sarhi, Jack, and Jones no longer holds, even if a nontrivial ...
openaire +2 more sources
Computational and Mathematical BiophysicsRecent studies have intensified the risk of post-COVID-19 cardiovascular diseases. In an effort to understand the intricate dynamics of COVID-19 infection, this article suggests a four-compartment model to portray the dynamic interplay between the ...
Shirisha Gopishetty, Vernekar Saroj
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Drama Forum : A Conversation with Marc Spitz '92 (Poster)
, 2016 1 poster : color, b&w photographEvent Poster. Marc Spitz '92, music journalist and playwright.
Spitz, Marc '92
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Superseded New Jersey Administrative Code: Title 10: Chapter 92
, 2008 Pages Removed:1-
New Jersey. Department of Human Services
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Journal of Biological DynamicsThroughout the last two centuries, vaccines have been helpful in mitigating numerous epidemic diseases. However, vaccine hesitancy has been identified as a substantial obstacle in healthcare management.
Indunil M. Hewage +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source