Results 31 to 40 of about 1,735,097 (247)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Bounding the generation time distribution uncertainty on R0 estimation from exponential growth rates

open access: yesJournal of Biological Dynamics
The basic reproduction number [Formula: see text] is one of the main parameters determining the spreading of an epidemic in a population of susceptible individuals.
James Cochran, Bogdan Oancea, Dan Pirjol
doaj   +1 more source

Rapid Voltammetric Screening Method for the Assessment of Bioflavonoid Content Using the Disposable Bare Pencil Graphite Electrode

open access: yesChemosensors, 2021
Hesperidin (HESP) is a plant bioflavonoid found in various nutritional and medicinal products. Many of its multiple health benefits rely on the compound’s antioxidant ability, which is due to the presence of oxidizable hydroxyl groups in its structure ...
Iulia Gabriela David   +6 more
doaj   +1 more source

Outstanding junior investigator program. [Final technical report, 8/1/92-10/31/97] [PDF]

open access: yes, 1999
Much of the authors work over the past five years has been aimed at bridging the gap between the exactly supersymmetric world of string theories and the world that is actually observed. Her report discusses the following subjects: (1) supersymmetry breaking; related work on the mass hierarchy and the relation between supersymmetry and grand unified ...
Randall, Lisa, Rosenberg, Leslie
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Identification of causal intervention effects under contagion

open access: yesJournal of Causal Inference, 2021
Defining and identifying causal intervention effects for transmissible infectious disease outcomes is challenging because a treatment – such as a vaccine – given to one individual may affect the infection outcomes of others. Epidemiologists have proposed
Cai Xiaoxuan   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

First records of the Indo-Pacific Finless Porpoise Neophocaena phocaenoides (G. Cuvier, 1829) (Cetartiodactyla: Phocoenidae) from Sri Lanka

open access: yesJournal of Threatened Taxa, 2017
Thirty species of marine mammals have been recorded from Sri Lanka.  Amongst them the Indo-Pacific Finless Porpoise Neophocaena phocaenoides is the only representative of the family Phocoenidae.
Ranil P. Nanayakkara   +2 more
doaj   +1 more source

Great Transformation on a Microscale: The Targowisko Settlement Region

open access: yesOpen Archaeology, 2022
The aim of the article is to characterize the well-recognized early Neolithic settlement region of Targowisko in SE Poland. It is located in southern Poland, on the northern outskirts of Western Carpathians, 30 km to the east of Krakow.
Golański Adam, Kadrow Sławomir
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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