Results 41 to 50 of about 10,447,998 (233)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Superseded New Jersey Administrative Code: Title 10: Chapter 92

open access: yes, 2003
Pages Removed:1-
New Jersey. Department of Human Services
core   +1 more source

First records of the Indo-Pacific Finless Porpoise Neophocaena phocaenoides (G. Cuvier, 1829) (Cetartiodactyla: Phocoenidae) from Sri Lanka

open access: yesJournal of Threatened Taxa, 2017
Thirty species of marine mammals have been recorded from Sri Lanka.  Amongst them the Indo-Pacific Finless Porpoise Neophocaena phocaenoides is the only representative of the family Phocoenidae.
Ranil P. Nanayakkara   +2 more
doaj   +1 more source

Great Transformation on a Microscale: The Targowisko Settlement Region

open access: yesOpen Archaeology, 2022
The aim of the article is to characterize the well-recognized early Neolithic settlement region of Targowisko in SE Poland. It is located in southern Poland, on the northern outskirts of Western Carpathians, 30 km to the east of Krakow.
Golański Adam, Kadrow Sławomir
doaj   +1 more source

Outstanding junior investigator program. [Final technical report, 8/1/92-10/31/97] [PDF]

open access: yes, 1999
Much of the authors work over the past five years has been aimed at bridging the gap between the exactly supersymmetric world of string theories and the world that is actually observed. Her report discusses the following subjects: (1) supersymmetry breaking; related work on the mass hierarchy and the relation between supersymmetry and grand unified ...
Randall, Lisa, Rosenberg, Leslie
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Immunoekspresja białka LAMP2 w ośrodkowym układzie nerwowym u osób chorych na sporadyczną postać choroby Creutzfeldta-Jakoba (sCJD)

open access: yesAktualności Neurologiczne, 2010
Wstęp: Sporadyczna postać choroby Creutzfeldta-Jakoba (sCJD) to śmiertelna choroba neurologiczna z grupy pasażowalnych encefalopatii gąbczastych (TSE). Ze względu na obecność polimorfizmu w kodonie 129.
Piotr Gębski, Beata Sikorska
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

'92 지역별 수출입 동향과 전망 1992. 5. 1.

open access: yes, 2020
I. '92 수출입 동향 II. 지역별 수출동향과 시장현황 III. 수출전망 종합 IV.

core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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