Results 71 to 80 of about 11,372,062 (345)
Comprehensive Psychiatry, 2019 Background: Despite the extensive research performed on prediction of psychosis from a Clinical High Risk for Psychosis state (CHR-P), the positive predictive value of the CHR-P designation remains unsatisfactory and further models including additional ...
Magdalena Kotlicka-Antczak +6 more
doaj
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
High level of interleukin-10 in serum predicts poor prognosis in multiple myeloma
British Journal of Cancer, 2016 Background:Interleukin-10 (IL-10) is a inhibiting inflammatory cytokine that plays an important role in immune suppressive microenvironment in multiple myeloma (MM).
Hua Wang +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Journal of Clinical Investigation, 1973 Endothelial cells were isolated from freshly obtained human umbilical cords by collagenase digestion of the interior of the umbilical vein. The cells were grown in tissue culture as a homogeneous population for periods up to 5 mo and some lines were ...
E. Jaffe +3 more
semanticscholar +1 more source
Äge E-viirushepatiit. Haigusjuhu kirjeldus [PDF]
, 2013 E-hepatiidi viirus avastati 1983. aastal. Kuni viimase ajani oldi arvamusel, et E-hepatiit on vaid endeemilistes piirkondades esinev haigus ja sellesse haigestutakse neid piirkondi külastades.
Pihlak, Rita +2 more
core +2 more sources
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Aktualności Neurologiczne, 2010 Wstęp: Sporadyczna postać choroby Creutzfeldta-Jakoba (sCJD) to śmiertelna choroba neurologiczna z grupy pasażowalnych encefalopatii gąbczastych (TSE). Ze względu na obecność polimorfizmu w kodonie 129.
Piotr Gębski, Beata Sikorska
doaj
Journal of Clinical Oncology, 2008 PURPOSE To determine whether adding 2 years of androgen-deprivation therapy (ADT) improved outcome for patients electively treated with ADT before and during radiation therapy (RT).
E. Horwitz +10 more
semanticscholar +1 more source