Background: Salmonella enterica and Escherichia coli are common foodborne pathogens of global concern, particularly due to their antimicrobial resistance, notably to cephalosporins.
Rujirat Hatrongjit +6 more
doaj +1 more source
Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
core +1 more source
Long‐Term Results of UPPP and Coblation Channeling of the Tongue for Obstructive Sleep Apnea
ABSTRACT Objective To evaluate the long‐term surgical outcomes of combined uvulopalatopharyngoplasty (UPPP) and coblation channeling of the tongue (CCT) for moderate‐to‐severe obstructive sleep apnea (OSA). Methods The study enrolled patients with moderate‐to‐severe OSA who underwent treatment with UPPP plus CCT and had a minimal follow‐up of 2 years ...
Ren‐Hui Chen +3 more
wiley +1 more source
Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]
This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon +15 more
core
ABSTRACT Siderophore cephalosporins are designed to exploit bacterial nutrient uptake systems to gain accelerated uptake across the outer membrane of Gram-negative bacteria. They contain iron (III) binding motifs that allow them to form complexes that will be recognized as potential substrates
openaire +2 more sources
Active Emergency Management of Adult Acute Epiglottitis: An Analysis of 570 Cases
ABSTRACT Objective Acute epiglottitis, which is primarily caused by bacterial infection, can quickly progress to life‐threatening airway obstruction. The first 24 h after symptom onset is a critical window for management. However, few studies have evaluated the effect of emergency management during this period or have identified the factors that ...
Bo‐Jun Shen +7 more
wiley +1 more source
Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]
The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa +5 more
core +1 more source
Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
This study included 28 amoxicillin‐allergic patients and 11 healthy exposed controls. Mast cells were differentiated from CD34+ progenitors over 8 weeks using cytokine cocktails. The mast cell activation test involved sensitization with patient or control sera and stimulation with free amoxicillin or G4/G5‐AXO dendrimers with successfully activated ...
Jose A. Céspedes +11 more
wiley +1 more source
Antibiotic susceptibility and high prevalence of extended spectrum beta-lactamase producing Escherichia coli in iranian broilers [PDF]
Extended-spectrum β-lactamase (ESBL) producing Escherichia coli have rapidly spread worldwide and cause serious threats for public health. The study was conducted to determine the antibiotic resistance and characterization of ESBL producing E.
Khoshbakht, R., Raeisi, M., Seifi, S.
core
Staphylococcus aureus, commonly colonising CTCL patients, augments skin barrier dysfunction. Staphylococcal enterotoxins induce T‐cell release of barrier‐repressing cytokines (IL‐4, IL‐13, IL‐22, OSM). Cytokine signalling drives JAK‐dependent downregulation of filaggrin and loricrin in keratinocytes. Antibiotic‐mediated eradication of S. aureus induces
Maria Gluud +23 more
wiley +1 more source

