Results 191 to 200 of about 268,148 (374)

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model

Nature Neuroscience, 2019
Peisu Zhang, Y. Kishimoto, Ioannis Grammatikakis, K. Gottimukkala, R. Cutler, Shiliang Zhang, K. Abdelmohsen, V. Bohr, Jyoti Misra Sen, M. Gorospe, M. Mattson   +10 more
semanticscholar   +1 more source

P3‐416: Differential TGF‐β‐Smad 2/3 and BMP‐Smad 1/5/8 pathway activation promotes macrophage Aβ phagocytosis [PDF]

, 2010
David Gate, Kavon Rezai‐Zadeh, Helen S. Goodridge, Javier Rodríguez, Dominique Jodry, David M. Underhill, Terrence Town   +6 more
openalex   +1 more source

Icariin Attenuates Amyloid-β (Aβ)-Induced Neuronal Insulin Resistance Through PTEN Downregulation [PDF]

, 2020
Xiaomei Zou, Xiyao Feng, Yalin Fu, Yuyang Zheng, Mingke Ma, Changhua Wang, Yemin Zhang   +6 more
openalex   +1 more source

Mucocutaneous disease activity and damage accrual in systemic lupus erythematosus: analyses from the Asia‐Pacific Lupus Collaboration longitudinal cohort study

Arthritis Care &Research, Accepted Article.
Objective This research article aims to describe the prevalence, associations and health‐related quality‐of‐life (HRQoL) impact of mucocutaneous features of SLE. Methods Data from the Asia‐Pacific Lupus Collaboration cohort were analysed (2013‐2021). Mucocutaneous activity (MC‐A) items were rash, alopecia and mucosal ulcers; defined by the SLEDAI‐2K ...
Amanda M Saracino, Yanjie Hao, Dylan Hansen, Yi‐Hsing Chen, Alberta Hoi, Vera Golder, Jiacai Cho, Aisha Lateef, Worawit Louthrenoo, Laniyati Hamijoyo, Shue Fen Luo, Yeong‐Jian Jan Wu, Sandra Navarra, Leonid Zamora, Chak Sing Lau, Shirley Chan, Zhanguo Li, Hai‐hong Yao, Sargunan Sockalingam, BMDB Basnayake, Yasuhiro Katsumata, Masayoshi Harigai, Zhuoli Zhang, Jun Kikuchi, Yuko Kaneko, Tsutomu Takeuchi, Madelynn Chan, Sang‐Cheol Bae, Fiona Goldblatt, Sean O'Neill, Geraldine Hassett, Kristine(Pek Ling) Ng, Nicola Tugnet, Mark Sapsford, Yih Jia Poh, Michael Tee, Cherica Tee, Naoaki Ohkubo, Yoshiya Tanaka, Rangi Kandane‐Rathnayake, Eric Morand, Shereen Oon, Mandana Nikpour   +42 more
wiley   +1 more source

Mapping lipids associated with Aβ plaques in a mouse model of Alzheimer’s disease via multiscale mass spectrometry imaging [PDF]

Timothy J. Trinklein, Stanislav S. Rubakhin, Marisa Asadian, K.R. Sabitha, Orly Lazarov, Fan Lam, Jonathan V. Sweedler   +6 more
openalex   +1 more source

Associations of Rheumatoid Arthritis Disease Activity with Frailty Over Five Years of Follow‐up

Arthritis Care &Research, Accepted Article.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis registry enrolled from 2003 to 2022 were included. The exposure was RA disease activity measured by Disease Activity Score in 28‐joints (DAS28)
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Pyroglutamate-modified Aβ(3-42) affects aggregation kinetics of Aβ(1-42) by accelerating primary and secondary pathways

, 2017
Christina Dammers, Melanie Schwarten, Alexander K. Buell, Dieter Willbold   +3 more
openalex   +2 more sources

Polyphenols Derived from Lychee Seed Suppress Aβ (1-42)-Induced Neuroinflammation [PDF]

, 2018
Yong Tang, Rui Xiong, Anguo Wu, Chong‐Lin Yu, Ya Zhao, Wenqiao Qiu, Xiuling Wang, Jin‐Feng Teng, Jian Liu, Hạixia Chen, Jianming Wu, Dalian Qin   +11 more
openalex   +1 more source

Obesity subtypes and longitudinal trajectories of function over 7‐years of follow‐up: data from the Multicenter Osteoarthritis Study

Arthritis Care &Research, Accepted Article.
Background Obesity, defined by BMI ≥30kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA.
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi   +6 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products used by Rheumatology Patients in Alberta: A Multivariable Analysis of Cross‐sectional Survey Data

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among rheumatology patients, and their associations with patient factors, patient reported perceived side effects and positive impacts. Methods An online survey (delivered from March to November 2022) was distributed by Alberta Health Services to ...
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source