Results 261 to 270 of about 268,148 (374)

The microtubule nexus linking amyloid beta and tau: A simple and unifying theory for the underlying cause of Alzheimer's disease. [PDF]

PNAS Nexus
Shoff TA, Derbez-Morin M, Cai P, Julian RR.   +3 more
europepmc   +1 more source

Inhibitors of Aβ production: solid-phase synthesis and SAR of α-hydroxycarbonyl derivatives

, 2003
Owen B. Wallace, David W. Smith, Milind Deshpande, Craig Polson, Kevin M. Felsenstein   +4 more
openalex   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Transcranial Ultrasound Stimulation Pulsed at 40 Hz Improves Cognition and Neuroinflammation in Female Mice with Alzheimer's Disease. [PDF]

Research (Wash D C)
Yi S, Zou J, He X, Chen H, Lin Z, Zhang L, Zhu Y, Zuo Z, Chen Z, Hu X, Niu L.   +10 more
europepmc   +1 more source

Arterial spin labeling imaging reveals widespread and Aβ-independent reductions in cerebral blood flow in elderly apolipoprotein epsilon-4 carriers [PDF]

, 2015
Lars Michels, Geoffrey Warnock, Alfred Buck, Gianluca Macauda, Sandra E. Leh, Andrea M. Kaelin, Florian Riese, Rafael Meyer, Ruth Tuura, Christoph Höck, Spyros Kollias, Anton Gietl   +11 more
openalex   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

Advanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova, Ivan V. Zelepukin, Lyubov V. Gorelik, Anton L. Popov, Andrei I. Pastukhov, Gleb V. Tikhonowski, Maxim S. Savinov, Danil D. Kolmanovich, Nikita A. Pivovarov, Alina Yu. Kapitannikova, Anton A. Popov, Anna S. Sogomonyan, Vsevolod A. Skribitsky, Aziz B. Mirkasymov, Andrei V. Kabashin, Sergey M. Deyev   +15 more
wiley   +1 more source

Health system patterns of imaging and fluid biomarker testing in the era of anti-amyloid therapies. [PDF]

Alzheimers Dement
Robb WH, Kaur G, Huang S, Martinez F, Nguyen B, Shin CH, Yang M, Conyers CT, Grilli CB, Upjohn DP, Ortega VE, Hohman TJ, Keegan RM, Parent EE, Cogswell PM, Graff-Radford J, Johnson DR, Ramanan VK, Koran ME.   +18 more
europepmc   +1 more source

Alzheimer's-Causing Mutations Shift Aβ Length by Destabilizing γ-Secretase-Aβn Interactions.

Cell, 2017
Maria Szaruga, B. Munteanu, Sam Lismont, Sarah Veugelen, Katrien Horré, M. Mercken, T. Saido, N. Ryan, T. De Vos, S. Savvides, R. Gallardo, J. Schymkowitz, F. Rousseau, N. Fox, C. Hopf, Bart de Strooper, Lucía Chávez‐Gutiérrez   +16 more
semanticscholar   +1 more source

Untersuchung externer und intrazellulärer Faktoren und Mechanismen auf den Bildungsprozess von Aβ-Amyloid

, 2011
Katharina Tepper
openalex   +1 more source

Molecular Dynamics Simulations of Ibuprofen Binding to Aβ Peptides [PDF]

, 2009
E. Prabhu Raman, Takako Takeda, Dmitri K. Klimov   +2 more
openalex   +1 more source