Results 41 to 50 of about 115,377,958 (292)

The evaluation of biological maturity in sport [PDF]

open access: yesSport - Nauka i Praksa, 2019
The aim of the paper is to present various methods for the evaluation of biological maturity which can define the differences between chronological age and biological maturity in young athletes.
Jovanović Jovan
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Future optimism group based on the chronological stress view is less likely to be severe procrastinators

open access: yesScientific Reports
Previous studies have shown that procrastinators tend to disregard the future. However, the "time view" of procrastinators, including their impressions of the future, has not been sufficiently examined.
Saya Kashiwakura, Kazuo Hiraki
doaj   +1 more source

Time In Cinema And Modern Art: Reflections Inspired By Farshad Zahedi’s 'The Petrified Object And The Poetics Of Time In Cinema'

open access: yesJournal of Science and Technology of the Arts, 2022
Inspired by Farshad Zahedi’s audiovisual essay The Petrified Object and the Poetics of Time in Cinema, this article briefly presents three philosophical approaches to cinema’s ways of expressing time – as articulated by Bergson, Tarkovsky, and Deleuze –
Susana Viegas
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

Aberrant aging-associated p62 autophagic cascade in biopsied olfactory neuronal cells from patients with psychosis

open access: yesSchizophrenia
Sequestosome-1/p62, a key mediator in the clearance of damaged organelles and macromolecules during autophagy, serves as a marker of biological aging. We demonstrate elevated p62 in biopsied neuronal cells in patients with psychosis compared to healthy ...
Kun Yang   +3 more
doaj   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Study on the mechanism of Cordyceps cicadae extracts promote longevity in Saccharomyces cerevisiae

open access: yes四川大学学报. 自然科学版, 2020
This study aims to explore the role of Cordyceps cicadae extracts (CCE) in resistance against H2O2 -induced oxidative stress and chronological lifespan extension in Saccharomyces cerevisiae.
YANG Li, YAN Meng-Li, LIU Ke
doaj  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Does operation order has impacts on postoperative complications in gastric cancer patients? A study of surgeon fatigue [PDF]

open access: yesKorean Journal of Clinical Oncology, 2016
Purpose There is a growing concern that accumulated fatigue due to extended working hours may contribute to poor surgical outcomes. This study aimed to compare postoperative complications of gastric cancer patients according to operation chronology in a ...
Jae Won Cho   +2 more
doaj   +1 more source

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