Results 91 to 100 of about 1,317,143 (303)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Crisis and Change: A University Press Environmental Scan

open access: yesJournal of Librarianship and Scholarly Communication, 2014
A transcript of the closing keynote address delivered March 6, 2014 at the inaugural Library Publishing Forum in Kansas City, Missouri.
Peter Berkery
doaj   +2 more sources

LO-Net: Deep Real-time Lidar Odometry

open access: yes, 2019
We present a novel deep convolutional network pipeline, LO-Net, for real-time lidar odometry estimation. Unlike most existing lidar odometry (LO) estimations that go through individually designed feature selection, feature matching, and pose estimation ...
Chen, Shaoyang   +6 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Heavy Vehicle Road Safety: A Scan of Recent Literature

open access: yesJournal of Road Safety, 2011
The number of registered heavy vehicles (HV) in Australia has risen by 22% since 2005 and, with the national freight task projected to double by 2030, the number of HVs on Australian roads will continue to increase.
S Raftery, J Grigo, J Woolley
doaj  

A Scanned Synthesis Virtual Instrument

open access: yes, 2002
This paper describes a virtual musical instrument based on the scanned synthesis technique and implemented in Max-Msp. The device is composed of a computer and three gesture sensors. The timbre of the produced sound is rich and changing. The instrument proposes an intuitive and expressive control of the sound thanks to a complex mapping between gesture
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Scan Chain Based Attacks and Countermeasures: A Survey

open access: yesIEEE Access, 2019
Scan chains increase the testability but decrease security. Attackers may use scan chains to launch attacks to obtain sensitive information, which poses serious security threats.
Xiaowei Li   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

On the Detectability of Galactic Dark Matter Annihilation into Monochromatic Gamma-rays

open access: yes, 2010
Monochromatic gamma-rays are thought to be the smoking gun signal for identifying the dark matter annihilation. However, the flux of monochromatic gamma-rays is usually suppressed by the virtual quantum effects since dark matter should be neutral and ...
Abdo A A   +17 more
core   +1 more source

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