Results 101 to 110 of about 1,317,143 (303)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Evaluating learning health systems: a jurisdictional scan

SSM - Health Systems
The Learning Health System (LHS) aims to improve healthcare by using continuous data analysis to create equitable, patient-centered, and cost-effective care.
Balpreet Panesar, Carly Whitmore, Shelley Vanderhout, Marissa Bird   +3 more
doaj   +1 more source

Search for Correlations between HiRes Stereo Events and Active Galactic Nuclei

, 2008
We have searched for correlations between the pointing directions of ultrahigh energy cosmic rays observed by the High Resolution Fly's Eye experiment and Active Galactic Nuclei (AGN) visible from its northern hemisphere location.
Abbasi, R. U., Abu-Zayyad, T., Allen, M., Amman, J. F., Archbold, G., Belov, K., Belz, J. W., BenZvi, S. Y., Bergman, D. R., Blake, S. A., Boyer, J. H., Brusova, O. A., Burt, G. W., Cannon, C., Cao, Z., Deng, W., Fedorova, Y., Findlay, J., Finley, C. B., Gray, R. C., Hanlon, W. F., Hoffman, C. M., Holzscheiter, M. H., Hughes, G., Huntemeyer, P., Ivanov, D., Jones, B. F, Jui, C. C. H., Kim, K., Kirn, M. A., Knapp, B. C., Loh, E. C., Maestas, M. M., Manago, N., Mannel, E. J., Marek, L. J., Martens, K., Matthews, J. N., Moore, S. A., O'Neill, A., Painter, C. A., Perera, L., Reil, K., Riehle, R., Roberts, M. D., Sasaki, D. Rodriguez N., Schnetzer, S. R., Scott, L. M., Seman, M., Sinnis, G., Smith, J. D., Snow, R., Sokolsky, P., Song, C., Springer, R. W., Stokes, B. T., Stratton, S. R., Thomas, J. R., Thomas, S. B., Thomson, G. B., Tupa, D., Wiencke, L. R., Zech, A., Zhang, X.   +63 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

PEEK Intraoral Scan Bodies—A Scoping Review

Dentistry Journal
Background: Accurate digital impressions are crucial for the long-term success of implant-supported prostheses, with scan bodies playing a pivotal role in transferring the implant position into the virtual model.
Ioulianos Rachiotis, Aspasia Pachiou, Daniel S. Thoma, Nadja Naenni, Christos Rahiotis   +4 more
doaj   +1 more source

Recent results from NA61/SHINE

, 2015
The NA61/SHINE experiment aims to discover the critical point of strongly interacting matter and study the properties of the onset of deconfinement. For these goals a scan of the two dimensional phase diagram (T-$\mu_B$) is being performed at the SPS by ...
Andronov, Evgeny
core   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

When the scan tells a different story

JEM Reports
Background: Point-of-care ultrasound (POCUS) has become a standard in emergency care for its rapid, accurate bedside diagnostics and procedural guidance.
Matthew S. Berniard, Monika Krzak, Richard Slama, Charles Dalton Hardesty, Carlo Zamora, Christina Cartwright   +5 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Quantum optical coherence tomography of a biological sample

, 2008
Quantum optical coherence tomography (QOCT) makes use of an entangled-photon light source to carry out dispersion-immune axial optical sectioning. We present the first experimental QOCT images of a biological sample: an onion-skin tissue coated with gold
Abouraddy, Bahaa E.A. Saleh, Banaszek, Björn M. Reinhard, Brezinski, Darryl P. Goode, Erkmen, Fercher, Fercher, Fercher, Guoxin Rong, Harris, Hayat, Hong, Huang, Kaltenbaek, Larchuk, Lee, Linglu Yang, Magde, Magued B. Nasr, Malvin C. Teich, Mandel, Marsili, Nam Nguyen, Nasr, Nasr, Nasr, Resch, Saleh, Saleh, Schmitt, Steinberg, Takada, Teich, Teich, Tomlins, Youngquist   +37 more
core   +1 more source