Results 41 to 50 of about 84,425,241 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Maternal PRDM10 activates essential genes for oocyte-to-embryo transition

open access: yesNature Communications
PR/SET domain-containing (PRDM) proteins are metazoan-specific transcriptional regulators that play diverse roles in mammalian development and disease. Several members such as PRDM1, PRDM14 and PRDM9, have been implicated in germ cell specification and ...
Michelle K. Y. Seah   +10 more
doaj   +1 more source

Stability of Graphs [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2009
Positively weighted graphs have a natural intrinsic metric. We consider finite, positively weighted graphs with a positive lower bound for their minimal weights and show that any two such graphs, which are close enough with respect to the Gromov-Hausdorff metric, are equivalent as graphs.
Bünyamin Demir, Ali Deniz, Sahin Koçak
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Maximal order of accuracy of (m, 1)-methods for solving stiff problems

open access: yesVestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2011
We investigate (m, 1)-methods for solving stiff problems in which the right part of system of the diааerential equations is calculated one times on each step. It is shown that the maximal order of accuracy of the L-stability (m, 1)-method is equal to two,
Evgeniy A Novikov
doaj  

Improved Stability of Amorphous InGaZnO4 Thin-Film Transistors Under Negative Bias Illumination Stress With Split Metal Cover Lines

open access: yesIEEE Journal of the Electron Devices Society
Negative bias illumination stress (NBIS) instability presents a significant challenge for the application of amorphous $\rm InGaZnO_{4}$ (a-IGZO) thin-film transistors (TFTs) in active-matrix displays.
Yuhan Feng   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

G-stability one-leg hybrid methods for solving DAEs

open access: yesAdvances in Difference Equations, 2019
This paper introduces the solution of differential algebraic equations using two hybrid classes and their twin one-leg with improved stability properties.
P. Agarwal   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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