Results 61 to 70 of about 84,425,241 (312)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Sharp global nonlinear stability for a fluid overlying a highly porous material [PDF]
, 2009 The stability of convection in a two-layer system in which a layer of fluid with a temperature-dependent viscosity overlies and saturates a highly porous material is studied. Owing to the difficulties associated with incorporating the nonlinear advection
A. A. Hill +3 more
core +1 more source
Stability of antioxidant vitamins in commercial vitamin supplements
Brazilian Journal of Pharmaceutical Sciences, 2019 The stability of vitamins A, E, and C was determined in 12 brands of vitamin supplements over a 12-month storage period. The variations in concentrations of these vitamins across three different batches of five brands were measured.
Lucile Tiemi Abe-Matsumoto +2 more
doaj +1 more source
Stability analysis of a mathematical model for the abatement of methane: Effect of mitigation options [PDF]
Computational Ecology and Software, 2021 Atmospheric methane is one of the main greenhouse gases which contribute significantly to increase the burden of global warming. The production of rice paddies and livestock farming are the major sources of methane emissions in the atmosphere.
Ashish Kumar Mishra +3 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Stability vs. complexity of ecosystems: a random matrix approach [PDF]
, 2022 openIn this thesis we investigate the complexity and stability of ecosystems using the random matrix theory. We start analyzing the approach of Robert May, whose work is considered one of the most influential in theoretical ecology.
CIOFFI, ERICA
core
CURRENT PROBLEMS TUBERCULOSIS EPIDEMIC SITUATION IN SOUTHERN RUSSIA, TRENDS AND PROSPECTS
Медицинский вестник Юга России, 2013 Purpose: the estimation of an epidemic situation on a tuberculosis in the south of Russia: in Southern and North Caucasian federal districts; revealing of the basic problems; definition of priority directions of the organization of struggle against a ...
L. A. Shovkun +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source