Results 21 to 30 of about 174,567 (285)

Therapeutic Oligonucleotides Targeting Liver Disease: TTR Amyloidosis

open access: yesMolecules, 2015
The liver has become an increasingly interesting target for oligonucleotide therapy. Mutations of the gene encoding transthyretin (TTR), expressed in vast amounts by the liver, result in a complex degenerative disease, termed familial amyloid ...
Christoph Niemietz   +2 more
doaj   +1 more source

La cultura del privilegio y la igualdad de derechos: antípodas por resolver en las democracias latinoamericanas

open access: yesEl Trimestre Económico, 2022
La confianza en interacciones sociales e instituciones democráticas en América Latina se ve erosionada por la persistencia de privilegios de grupos que perpetúan brechas de clase en acceso a activos, capital cultural, redes de relaciones, apropiación de ...
Martín Hopenhayn
doaj   +1 more source

Non-deletion mutations in Egyptian patients with Duchenne muscular dystrophy

open access: yesEgyptian Journal of Medical Human Genetics, 2014
Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophies affecting approximately 1:3500 male live births. Deletion of the dystrophin gene accounts for approximately 65% of mutations, duplications occur in 6–10% while the ...
Rabah M. Shawky   +5 more
doaj   +1 more source

Progress of hepatitis B virus-associated neutralizing antibody in antiviral therapy of chronic hepatitis B [PDF]

open access: yesXin yixue, 2022
Chronic hepatitis B virus infection is not only an important global public health problem but also an important challenge in our country. Although there are some vaccines for hepatitis B and its prevalence is increasing year by year, there are still many
Zhao Yudi, Huang Mingxing
doaj   +1 more source

The Archipelago of Cultural and Creative Industries: A Case Study of the Basque Country

open access: yesEconomies, 2020
The cultural and creative industries (e.g., digital/audiovisual content, publishing and print media, etc.) constitute an emerging business sector focused on aligning cultural and creative production with profitability and market criteria that encompasses
Xabier Barandiaran-Irastorza   +2 more
doaj   +1 more source

Transfer matrix eigenvectors of the Baxter-Bazhanov-Stroganov $\tau_2$-model for N=2 [PDF]

open access: yes, 2005
We find a representation of the row-to-row transfer matrix of the Baxter-Bazhanov-Stroganov $\tau_2$-model for N=2 in terms of an integral over two commuting sets of grassmann variables.
Baxter R J   +11 more
core   +2 more sources

Type II supernovae as probes of environment metallicity: observations of host HII regions [PDF]

open access: yes, 2016
Spectral modelling of SNII atmospheres indicates a clear dependence of metal line strengths on progenitor metallicity. This motivates further work to evaluate the accuracy with which these SNe can be used as metallicity indicators.
Anderson, J. P.   +12 more
core   +4 more sources

Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N‐terminal Inhibitors Without Induction of Heat Shock Response

open access: yesChemistryOpen, 2019
Heat shock protein 90 (Hsp90) is a potential oncogenic target. However, Hsp90 inhibitors in clinical trial induce heat shock response, resulting in drug resistance and inefficiency.
Dr. Peng Liu   +12 more
doaj   +1 more source

Type II supernova spectral diversity, II: spectroscopic and photometric correlations [PDF]

open access: yes, 2017
We present an analysis of observed trends and correlations between a large range of spectral and photometric parameters of more than 100 type II supernovae (SNe II), during the photospheric phase.
Anderson, Joseph P.   +9 more
core   +5 more sources

Mapping and Damage Assessment of “Royal” Burial Mounds in the Siberian Valley of the Kings

open access: yesRemote Sensing, 2020
The Valley of the Kings in Tuva Republic, southern Siberia, is arguably one of the most important archaeological landscapes in the eastern Eurasian steppes.
Gino Caspari
doaj   +1 more source

Home - About - Disclaimer - Privacy