Results 1 to 10 of about 817 (101)
A Michaelis-Arbuzov-Type Pathway to a Protected 2'-Deoxy-2'-Selenomethyl-Adenosine-3',5'-Phosphoroselenolate Guanosine Dinucleotide for Use in Modified m7G Cap Synthesis. [PDF]
ChemistryHere we report a synthesis of the dinucleotide 4 for a projected future total synthesis of the m7G cap 1. Highlights of the route include: 1) a 3ʹ‐H‐phosphonate/5ʹ‐selenocyanate Michaelis‐Arbuzov coupling to forge the 3ʹ,5ʹ‐phosphoroselenolate; 2) an Amosova reductive selenomethylation to install the 2ʹ‐SeMe; 3) a solid CPR II 5ʹ‐O‐phosphitylation; and
Hale KLE, McCarthy HO, McLaughlin MG.
europepmc +2 more sources
Back to the Electrofuture: Named Reactions Powered by Electroorganic Syntheses. [PDF]
ChemSusChemBridging classical named reactions with modern electroorganic chemistry, this review presents how electrochemical strategies can revive and reinterpret historically significant transformations, highlighting their emerging potential as sustainable alternatives in contemporary organic synthesis.
Maiti D, Heo Y, Kang G, Kim M, Choi I.
europepmc +2 more sources
Self-Assembly of a Customizable Library of Nickel Trifluoromethylation Catalysts via Selective C─F and C─O Bond Cleavage. [PDF]
Angew Chem Int Ed EnglCarbatranes and anionic pincer ligands were self‐assembled via one‐pot C─F or C─O bond cleavage and the formation of C─O, C─N, or C─C bonds, forming ligand architectures inaccessible by common synthetic methods. This approach allowed to build a customizable library of nickel catalysts for light‐induced C─H bond trifluoromethylation.
Sorvanov A +5 more
europepmc +3 more sources
1,2,3-Triazoles as leaving groups in SNAr–Arbuzov reactions: synthesis of C6-phosphonated purine derivatives [PDF]
Beilstein Journal of Organic Chemistry, 2021 A new method for C–N bond transformations into C–P bonds was developed using 1,2,3-triazoles as leaving groups in SNAr–Arbuzov reactions. A series of C6-phosphonated 2-triazolylpurine derivatives was synthesized for the first time, with the isolated yields reaching up to 82% in the C–P-bond-forming event.
Kārlis-Ēriks Kriķis +3 more
openaire +3 more sources
FACILITATION OF CHORUS ROLE IN A. N. ARBUZOV’S PARABLE “THE HAPPY DAYS OF AN UNHAPPY MAN” [PDF]
Philology. Theory & Practice, 2018 The article is devoted to the analysis of the facilitated image of the chorus and its functions in the parable “The Happy Days of an Unhappy Man”, which was written by the Soviet playwright A. N. Arbuzov in 1967. It is proved that in the play the playwright simplifies the role of the chorus, facilitates its presence on the stage.
openaire +1 more source
Chemistry–Methods, Volume 6, Issue 7, July 2026.The esterification of phosphinic, phosphonic, and phosphoric acids is not possible due the high enthalpy of activation. However, the barrier may be overcome under MW irradiation to give phosphinates, phosphonates, and alkoxyphosphoric acids, respectively. In the latter cases, the remaining P(O)OH group was esterified by alkylation.
György Keglevich
wiley +1 more source
Engineering Functional Graphenic Materials for Bone Repair
WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 4, July/August 2026.Graphene oxide (GO) and its derivatives have many favorable properties for biomedical applications. This is due to the inherent properties of GO including high surface area, functionalizability, mechanical strength, and bioresorbable nature, among other properties outlined above.
Sebastian Guajardo +4 more
wiley +1 more source
Chemical Syntheses of 3′ and 5′ Phosphorylated Oligonucleotides: An Overview
European Journal of Organic Chemistry, Volume 29, Issue 21, 4 June 2026.This review provides an overview of the various chemical methods employed in the synthesis of oligonucleotides bearing a phosphate group at their 3′ or 5′ end. Notably, it presents modified phosphoramidites and supports developed for this purpose. Oligonucleotides (ON) with a phosphate monoester group at their 3′ or 5′ end have applications in many ...
Rémy Lartia
wiley +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 15, 22 April 2026.Threefold reduction of 9,10,11‐triptindanetrione with LiAlH4 or NaBH4 yields exclusively the C3‐symmetric triol, suggesting an intracomplex (“rolling”) mechanism. However, use of LiAlH4/LiAlD4 (1 : 1) reveals a preceding hydride exchange. Mechanistic implications are discussed including the reduction of the related diketone.
Thorsten Hackfort +5 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 28, Issue 48, December 22, 2025.Ready access to six‐membered phosphorus heterocycles through copper‐catalyzed intramolecular hydrophosphorylation of ortho‐alkynyl secondary phosphine oxides is described. The reaction proceedes with high regio‐ and stereoselectivity. An atom‐economic copper‐catalyzed intramolecular hydrophosphorylation of ortho‐alkynyl secondary phosphine oxides ...
Hamdi Sanaa +3 more
wiley +1 more source