Results 11 to 20 of about 117,935,502 (148)

1,2,3-Triazoles as leaving groups in SNAr–Arbuzov reactions: synthesis of C6-phosphonated purine derivatives [PDF]

Beilstein Journal of Organic Chemistry, 2021
A new method for C–N bond transformations into C–P bonds was developed using 1,2,3-triazoles as leaving groups in SNAr–Arbuzov reactions. A series of C6-phosphonated 2-triazolylpurine derivatives was synthesized for the first time, with the isolated ...
Maris Turks, Irina Novosjolova, Anatoly Mishnev   +2 more
exaly   +4 more sources

A Michaelis-Arbuzov-Type Pathway to a Protected 2'-Deoxy-2'-Selenomethyl-Adenosine-3',5'-Phosphoroselenolate Guanosine Dinucleotide for Use in Modified m7G Cap Synthesis. [PDF]

Chemistry
Here we report a synthesis of the dinucleotide 4 for a projected future total synthesis of the m7G cap 1. Highlights of the route include: 1) a 3ʹ‐H‐phosphonate/5ʹ‐selenocyanate Michaelis‐Arbuzov coupling to forge the 3ʹ,5ʹ‐phosphoroselenolate; 2) an Amosova reductive selenomethylation to install the 2ʹ‐SeMe; 3) a solid CPR II 5ʹ‐O‐phosphitylation; and
Hale KLE, McCarthy HO, McLaughlin MG.
europepmc   +2 more sources

Back to the Electrofuture: Named Reactions Powered by Electroorganic Syntheses. [PDF]

ChemSusChem
Bridging classical named reactions with modern electroorganic chemistry, this review presents how electrochemical strategies can revive and reinterpret historically significant transformations, highlighting their emerging potential as sustainable alternatives in contemporary organic synthesis.
Maiti D, Heo Y, Kang G, Kim M, Choi I.
europepmc   +2 more sources

Self-Assembly of a Customizable Library of Nickel Trifluoromethylation Catalysts via Selective C─F and C─O Bond Cleavage. [PDF]

Angew Chem Int Ed Engl
Carbatranes and anionic pincer ligands were self‐assembled via one‐pot C─F or C─O bond cleavage and the formation of C─O, C─N, or C─C bonds, forming ligand architectures inaccessible by common synthetic methods. This approach allowed to build a customizable library of nickel catalysts for light‐induced C─H bond trifluoromethylation.
Sorvanov A, Deolka S, Khaskin E, Fayzullin RR, Vasylevskyi S, Khusnutdinova JR.   +5 more
europepmc   +3 more sources

Dynamics of Clinical Manifestations and Social Functioning in Schizophrenia: A Non-interventional Observational Study of Paliperidone Palmitat Dosage Forms [PDF]

Consortium Psychiatricum
BACKGROUND: Over the past seven years, the use of long-acting forms of antipsychotic medication has significantly increased in Russia. Specifically, in Moscow, from 2016 to 2021, the proportion of prescribed injectable long-acting antipsychotics had ...
Aleksandr M. Reznik, Olga A. Karpenko, Elena A. Shumakova, Aleksandr V. Mudrak, Andrey V. Sokolov, Svetlana V. Nazimova, Alina M. Saifulina, Anton M. Eliseenko, Tatjana K. Matvievskaya, Angelina N. Khannanova, Vladimir I. Revenko, Dmitriy V. Scherbakov, Yuriy L. Martynyuk, Aleksandr L. Arbuzov, Oleg A. Yacenko, Polina N. Alekseeva, Aleksandr B. Berdalin, Larisa A. Burygina   +17 more
doaj   +2 more sources

N/A [PDF]

N/AA presente investigação surge da necessidade de reflexão no que toca ao papel desempenhado pelo Serviço Social quanto ao desenvolvimento, e à importância atribuída à autonomia na transição para a vida adulta na diversidade funcional.
Rodrigues da Silva, Patrícia Alexandra
core   +5 more sources

Structures of a Phosphoryl Derivative of 4-Allyl-2,4-dihydro-3H-1,2,4-triazole-3-thione: An Illustrative Example of Conformational Polymorphism

Crystals, 2021
Two polymorphic forms of a conformationally flexible molecule, 5-[(Diphenylphosphoryl)methyl]-4-(prop-2-en-1-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione, were obtained by crystallization and characterized by X-ray diffraction analysis and differential ...
Ivan V. Fedyanin, Aida I. Samigullina, Ivan A. Krutov, Elena L. Gavrilova, Dmitry V. Zakharychev   +4 more
doaj   +1 more source

Thymine-Modified Nanocarrier for Doxorubicin Delivery in Glioblastoma Cells

Molecules, 2023
Brain tumor glioblastoma is one of the worst types of cancer. The blood–brain barrier prevents drugs from reaching brain cells and shields glioblastoma from treatment.
Albina Y. Ziganshina, Elina E. Mansurova, Alexandra D. Voloshina, Anna P. Lyubina, Syumbelya K. Amerhanova, Marina M. Shulaeva, Irek R. Nizameev, Marsil K. Kadirov, Leysan R. Bakhtiozina, Vyacheslav E. Semenov, Igor S. Antipin   +10 more
doaj   +1 more source

Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate

Molbank, 2022
Diethyl 1-(N-acetylamino)-1-(diphenylphosphinoyl)-1-phenylmethylphosphonate was synthesized at room temperature, starting from 1-ethoxy derivative of diethyl 1-(N-acetylamino)-1-phenylmethylphosphonate via the corresponding phosphonium salt as a reactive
Anna Kuźnik, Dominika Kozicka, Jakub Adamek   +2 more
doaj   +1 more source

The Arbuzov Studio (1938–1945): Gaideburov’s Trace [PDF]

, 2023
This research focuses on the influence that the pedagogical work of P.P. Gaideburov and N.F. Skarskaya, the directors of the Peredvizhny Public Theatre, had in the 1920s on the activities of the Moscow State Theatre Studio run by Aleksei Arbuzov and ...
Mashukova Аlexandra V.
core   +2 more sources