Results 81 to 90 of about 113,964,602 (275)

Homophily‐adjusted social influence estimation

Canadian Journal of Statistics, EarlyView.
Abstract Homophily and social influence are two key concepts of social network analysis. Distinguishing between these phenomena is difficult, and approaches to disambiguate the two have been primarily limited to longitudinal data analyses. In this study, we provide sufficient conditions for valid estimation of social influence through cross‐sectional ...
Hanh T.D. Pham, Daniel K. Sewell
wiley   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Abordagens freqüentista e bayesiana para avaliação genética de bovinos da raça Canchim para características de crescimento Frequentist and bayesian approachs for genetic evaluation of Canchim beef cattle for growth traits

Revista Brasileira de Zootecnia, 2007
Este trabalho foi realizado com os objetivos de: a) comparar os componentes de (co)variância obtidos por meio dos métodos da Máxima Verossimilhança Restrita (REML) e da inferência bayesiana (IB); b) realizar a avaliação genética do peso à desmama (P240 ...
Fábio Luiz Buranelo Toral, Maurício Mello de Alencar, Alfredo Ribeiro de Freitas   +2 more
doaj   +1 more source

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, EarlyView.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

O ativismo judicial e constrangimentos a posteriori

Revista de Investigações Constitucionais, 2018
O presente artigo se propõe a analisar o ativismo judicial, expressão de significado impreciso e fugidio no nosso Direito. Após estabelecer algumas premissas para a definição teórica do ativismo judicial, passa a analisar, ainda no campo teórico, que o ...
Luiz Henrique Diniz Araújo
doaj   +1 more source

Adapting to Water Scarcity in Mediterranean Greenhouse Agriculture: Insights From Digital Irrigation and Regulated Water Governance in Southeastern Spain

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Climate‐driven water scarcity is compounding adaptation pressures on Mediterranean greenhouse farming, particularly for small and micro agricultural firms governed by regulated water‐governance systems. This paper analyses differentiated adaptation profiles in Almería (Spain) based on an analysis of farm structure, digital irrigation adoption,
Luis J. Belmonte‐Ureña, Francisco Camacho‐Ferre, Francisco José Castillo‐Díaz   +2 more
wiley   +1 more source

Bridging the Gap Between Human Toxicology and Ecotoxicology Under One Health Perspective by a Cross‐Species Adverse Outcome Pathway Network for Reproductive Toxicity

Environmental Toxicology and Chemistry, EarlyView.
Cross‐species extrapolation of adverse outcome pathway network on reproductive toxicity under the One Health perspective using new approach methodologies. AOP = adverse outcome pathway. Abstract Although ecotoxicological and toxicological risk assessments are performed separately from each other, recent efforts have been made in both disciplines to ...
Elizabeth Dufourcq Sekatcheff, Jaeseong Jeong, Jinhee Choi   +2 more
wiley   +1 more source

The prevalence of Streptococcus equi subsp. equi carriers in the Netherlands

Equine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies equi (S. equi) carriers are thought to be important drivers for strangles outbreaks. Limited data are available on the prevalence of carriers in European horse husbandry settings. Objectives To estimate the prevalence of S.
R. M. A. C. Houben, E. M. Broens, M. J. Broekhuizen‐Stins, M. M. Sloet van Oldruitenborgh‐Oosterbaan, C. van Maanen, J. A. P. Heesterbeek   +5 more
wiley   +1 more source

Unveiling Dental Students’ Baseline Self‐Regulated Learning Skills During an Authentic Diagnostic Reasoning Task

Journal of Dental Education, EarlyView.
ABSTRACT Purpose/Objectives This study aimed to cross‐culturally adapt and gather validity evidence for two instruments—the Self‐Regulated Learning Microanalytic Assessment (SRL‐MA) and the Assessment of Reasoning Tool—Reconstructed (ART‐R)—for assessing dental students' baseline self‐regulated learning (SRL) skills and diagnostic reasoning performance
Lorena Isbej, Dominique Waterval, Arnoldo Riquelme, Claudia Véliz, Ana Andaur, Paulina Freire, Anique B. H. de Bruin   +6 more
wiley   +1 more source

Impact of toothbrush type and periodontal phenotype on root coverage stability: A 6‐year observational follow‐up of a randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background This 6‐year observational follow‐up of a randomized, parallel‐arm clinical trial evaluated the association between toothbrush type and periodontal phenotype on the long‐term stability of the gingival margin (GM) following coronally advanced flap (CAF) surgery.
Raffaele Acunzo, Enrico Limiroli, Silvia Ricoboni, Giorgia Saracino, Giulio Rasperini   +4 more
wiley   +1 more source