Results 181 to 190 of about 617,829 (273)

Should we synthesize more than we need: impact of synthetic data generation for high-dimensional cross-sectional medical data. [PDF]

J Am Med Inform Assoc
Pilgram L, El Kababji S, Liu D, El Emam K.   +3 more
europepmc   +1 more source

Back Again to the Future: A New Era for Cerebroprotection

Annals of Neurology, EarlyView.
Cerebroprotection is a fresh framework for designing neurological therapy that targets glia and vascular cells, in addition to neurons. In the future, successful cerebroprotection will involve targeting all elements of the neurovascular unit. Preclinical trials must include functional outcomes, as well as lesion morphometry.
Patrick Lyden
wiley   +1 more source

Individual-Level, Multi-Provincial Analysis of High Temperature and Heat-Related Illness Association - China, 2013-2022. [PDF]

China CDC Wkly
Wang Z, Ma R, Wang X, Mo F, Zhao Y, Geng Y, Liu Y, Wei X, He M.   +8 more
europepmc   +1 more source

Prospective, Multicenter Evaluation of Transcarotid Artery Revascularization in Standard‐Risk Patients: 30‐Day Outcomes of the ROADSTER 3 Study

Annals of Neurology, EarlyView.
Objective To evaluate the real‐world safety and efficacy for standard surgical risk patients with extracranial internal carotid artery disease undergoing transcarotid artery revascularization. Methods ROADSTER 3 is a prospective, multicenter, single‐arm post‐approval study.
Jeffrey Jim, Meghan Dermody, Brian Peterson, Scott S. Berman, Nicolas J. Mouawad, Joseph Ricotta, Naveed Saqib, Peter Faries, Angela Martin, Joshua D. Adams, Uttam Tripathy, Daniel Calderon, David O'Connor, Rasesh Shah, Sumaira Macdonald, Marc L. Schermerhorn   +15 more
wiley   +1 more source

Building Molecules by a Self‐Replicator That Catalyzes Acyl Hydrazone Formation

Angewandte Chemie, EarlyView.
A self‐replicator efficiently catalyzes the formation of acyl hydrazone bonds between a set of different substrates. In addition to previously reported (bond‐breaking) catalytic activity, this renders the self‐replicator highly promiscuous, which is a good starting point for Darwinian experiments en route to de‐novo life.
Kayleigh S. van Esterik, Tommaso Marchetti, Sijbren Otto   +2 more
wiley   +2 more sources

Bayesian enrollment modeling for several emergency medicine clinical trials. [PDF]

Trials
Beall J, Yeatts SD, Silbergleit R, Shutter L, Korley F, Gajewski B.   +5 more
europepmc   +1 more source

DNase1 RS1053874 Polymorphism is Associated with Early Neurological Recovery through NET Modulation and with Long‐Term Survival in Ischemic Stroke: A Prospective Cohort Study

Annals of Neurology, EarlyView.
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito, P. Calleja, L. Alzamora, A. Ruiz‐García, A. Martínez‐Salio, M. Muñoz‐García, F. Ostos, A. García‐Culebras, A. Moraga, M.A. Moro, I. Lizasoain   +10 more
wiley   +1 more source

Dual Chemical Looping/Catalytic Process for Alkylation of Benzene With Ethane and Propane Yielding Ethylbenzene and Cumene Over Copper‐Containing Mordenite

Angewandte Chemie, EarlyView.
We report a dual chemical looping/catalytic process coupling alkane dehydrogenation with aromatic alkylation over Cu‐mordenite, yielding up to 25% alkylated aromatics with >95% selectivity per cycle. In situ NMR, FTIR spectroscopy, and DFT show alkylation proceeds via a π‐bound Cu(I)–olefin intermediate and Brønsted acid sites.
Florent J. Dubray, Yu‐Hsun Wang, Mikalai A. Artsiusheuski, Jiawei Guo, Rene Verel, Ambarish Kulkarni, Jeroen A. van Bokhoven, Vitaly L. Sushkevich   +7 more
wiley   +2 more sources

Oral rotavirus vaccine effectiveness among malnourished children in 19 countries: Findings from the MNSSTER-V project. [PDF]

J Pediatr Gastroenterol Nutr
Burnett E, Ticklay I, Umana J, Mandomando I, Robinson AL, Omore R, Goldfarb DM, Safi N, Trang NV, Kisakye A, Uwimana J, N'Zue K, Groome MJ, Enweronu-Laryea C, Bonkoungou I, Iniguez V, McCracken J, Lungayo CL, Michael F, Sahakyan G, Rey-Benito G, Weldegebriel G, Mwenda JM, Parashar UD, Tate JE, Multi‐national Subpopulations Study to Evaluate Rotavirus Vaccines (MNSSTER‐V) Project Working Group.   +25 more
europepmc   +1 more source

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source