The human AAA-ATPase VPS4A isoform and its co-factor VTA1 have a unique function in regulating mammalian cytokinesis abscission. [PDF]
PLoS BiolDvilansky I +4 more
europepmc +1 more source
Myopathy associated BAG3 mutations lead to protein aggregation by stalling Hsp70 networks [PDF]
, 2018 Bengoechea, Rocio, Weihl, Conrad C.
core +1 more source
Functional analysis of the Arabidopsis At1g64110 AAA+ATPase
Das Gen At1g64110 aus Arabidopsis thaliana stammt aus einer kleinen Gruppe von Genen die für AAA+ATPasen codieren zu denen auch At5g52882 und At4g28000 zählen. Es wurde gezeigt, dass At1g64110 in Synzytien, ein vom Zysten Nematoden Heterodera schachtii induziertes Nährgewebe in den Wurzeln, stark exprimiert wird.
openaire
Deficiency of MecA in Streptococcus mutans causes major defects in cell envelope biogenesis, cell division, and biofilm formation [PDF]
, 2018 Beatty, Wandy L +4 more
core +1 more source
Related searches:
RUVBL1-RUVBL2 AAA-ATPase: a versatile scaffold for multiple complexes and functions.
Current Opinion in Structural Biology, 2020RUVBL1 and RUVBL2 are two highly conserved AAA+ ATPases that form a hetero-hexameric complex that participates in a wide range of unrelated cellular processes, including chromatin remodeling, Fanconi Anemia (FA), nonsense-mediated mRNA decay (NMD), and ...
Maria I. Dauden +2 more
semanticscholar +1 more source
Holliday junction branch migration driven by AAA+ ATPase motors
Current Opinion in Structural Biology, 2023Holliday junctions are key intermediate DNA structures during genetic recombination. One of the first Holliday junction-processing protein complexes to be discovered was the well conserved RuvAB branch migration complex present in bacteria that mediates an ATP-dependent movement of the Holliday junction (branch migration).
Jiri Wald, Thomas C. Marlovits
openaire +3 more sources
The AAA team: related ATPases with diverse functions
Trends in Cell Biology, 1998A new family of related ATPases has emerged, characterized by a highly conserved AAA motif. This motif forms a 230-amino-acid domain that contains Walker homology sequences and imparts ATPase activity. Homology between AAA-family members is confined mostly to the AAA domain, although additional homology outside the AAA motif is present among closely ...
S, Patel, M, Latterich
openaire +3 more sources
AAA+ ATPases in the Initiation of DNA Replication
Critical Reviews in Biochemistry and Molecular Biology, 2008All cellular organisms and many viruses rely on large, multi-subunit molecular machines, termed replisomes, to ensure that genetic material is accurately duplicated for transmission from one generation to the next. Replisome assembly is facilitated by dedicated initiator proteins, which serve to both recognize replication origins and recruit requisite ...
Karl E, Duderstadt, James M, Berger
openaire +2 more sources
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle
Nature Structural Biology, 2002p97 (also called VCP), a member of the AAA ATPase family, is involved in several cellular processes, including membrane fusion and extraction of proteins from the endoplasmic reticulum for cytoplasmic degradation. We have studied the conformational changes that p97 undergoes during the ATPase cycle by cryo-EM and single-particle analysis.
Isabelle, Rouiller +6 more
openaire +2 more sources