Results 1 to 10 of about 70 (65)
European Respiratory Journal, 2003 Pulmonary emphysema is a major component of the morbidity and mortality of chronic obstructive pulmonary disease (COPD), a condition that has become the fourth leading cause of death in the USA, and is becoming epidemic worldwide. Emphysema is defined as enlargement of peripheral airspaces of the lung including respiratory bronchioles, alveolar ducts ...
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Nature, 1957 IT was shown by Linderstrom-Lang and co-workers1 that the tryptic hydrolysis of β-lactoglobulin involves the reversible denaturation of the protein as a preliminary stage. A consideration of known facts, together with new evidence obtained in connexion with an investigation of the mechanism of bating of skins in leather manufacture2, indicates that ...
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Regulated Proteolysis in Bacteria [PDF]
Annual Review of Biochemistry, 2018 Regulated proteolysis is a vital process that affects all living things. Bacteria use energy-dependent AAA+ proteases to power degradation of misfolded and native regulatory proteins. Given that proteolysis is an irreversible event, specificity and selectivity in degrading substrates are key.
Samar A, Mahmoud, Peter, Chien
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Pakistan Journal of Biological Sciences, 2001 In this research, the degree of proteolysis and correlations among the casein fractions, pH, soluble nitrogen, and ripening index in Golot cheese were investigated.
Yazici, F., Dervisoglu, M.
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Annals of Botany, 1902 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
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Proteolysis-Driven Oncogenesis [PDF]
Cell Cycle, 2007 An elevated expression of matrix metalloproteinases (MMPs) has been correlated with the growth and metastasis of preexisting tumors. The latest data, however, suggest that MMPs, by promoting genomic instability, are directly involved in the early stages of cell transformation from normalcy to malignancy and in incipient cancer.
Vladislav S, Golubkov, Alex Y, Strongin
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Proteolysis in hyperthermophilic microorganisms [PDF]
Archaea, 2002 Proteases are found in every cell, where they recognize and break down unneeded or abnormal polypeptides or peptide‐based nutrients within or outside the cell. Genome sequence data can be used to compare proteolytic enzyme inventories of different organisms as they relate to physiological needs for protein modification and hydrolysis.
Donald E, Ward +6 more
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Intramembrane Proteolysis of Astrotactins [PDF]
Journal of Biological Chemistry, 2017 Astrotactins are vertebrate-specific membrane proteins implicated in neuron-glia interactions during central nervous system development and in hair follicle polarity during skin development. By studying epitope-tagged derivatives of mouse astrotactin-2 (Astn2) produced in transfected cells, we determined that the amino and carboxyl termini reside in ...
Hao, Chang +3 more
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Phosphorylation Meets Proteolysis [PDF]
Structure, 2012 Phosphorylation is a reversible post-translational modification that regulates many proteins and enzymes, including proteases, as shown by two recent publications. Huang and colleagues and Velázquez-Delgado and Hardy (this issue of Structure) describe how phosphorylation activates the protease activity of the deubiquitinating enzyme DUBA and how it ...
Renatus, Martin, Farady, Christopher J.
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