Results 211 to 220 of about 133,715 (328)

A high‐throughput bone marrow 3D co‐culture system to study resistance to BCR signalling targeted agents in B‐NHL

open access: yesBritish Journal of Haematology, EarlyView.
Bone marrow (BM) involvement in B‐cell non‐Hodgkin lymphoma (B‐NHL) is associated with poor prognosis, as the BM microenvironment provides a protective niche that promotes therapeutic resistance. We developed a simplified, automated and high‐throughput 3D BM co‐culture model that faithfully reproduces key tumour–stroma interactions.
Alex Zadro   +12 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma   +9 more
wiley   +1 more source

Changes in gastrointestinal motility and gut hormone secretion after Roux‐en‐Y gastric bypass and sleeve gastrectomy for individuals with severe obesity

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Background Bariatric surgery is very effective in long‐term weight management. The present study was undertaken to investigate the short‐term effects of sleeve gastrectomy (SG) and of Roux‐en‐Y gastric bypass (RYGB) on (a) gastrointestinal (GI) motility, that is gastric emptying and oro‐cecal transit time and (b) secretion of regulatory gut ...
Jennifer A. Wilbrink   +4 more
wiley   +1 more source

Impact of early-life human microbiota on the murine host metabolome: insights from a two-generation HMA mouse model and implications for allergic disease. [PDF]

open access: yesBMC Microbiol
de Jong YA   +15 more
europepmc   +1 more source

Engineering Thermo-Responsive Hydrogels with Tailored Mechanics for Biomedical Integration. [PDF]

open access: yesPolymers (Basel)
Choi S   +8 more
europepmc   +1 more source

What Museum Guests Think About When They Think About Belonging

open access: yesCurator: The Museum Journal, EarlyView.
ABSTRACT A sense of belonging is one of the most fundamental human needs and is threaded through all aspects of a museum guest's experience. Using a previously validated model and survey of belonging in museums, we surveyed 1780 guests leaving eight different museums and similar cultural institutions across the United States.
C. Aaron Price   +3 more
wiley   +1 more source

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