Results 321 to 330 of about 144,727 (384)

Alcohol consumption and incident heart failure in men and women

European Journal of Heart Failure, EarlyView.
Alcohol consumption and incident heart failure (HF) in men and women. Abstract Aims Regular heavy alcohol consumption may lead to the development of alcohol‐related cardiomyopathy and symptomatic heart failure (HF) later in life. However, the dose–response relationship between alcohol consumption and risk for incident HF, and whether these associations
Hailun Qin, Bart J. van Essen, Jozine M. ter Maaten, Adriaan A. Voors   +3 more
wiley   +1 more source

Regulating astrocytic activity in the dorsal striatum mitigates L-dopa-induced dyskinesia in Parkinson's disease. [PDF]

Sci Rep
Ryu YK, Park HY, Kim JE, Seo HH, Lee CH, Kim KS.   +5 more
europepmc   +1 more source

847. Cytotoxic Immune Response Following Retroviral-Mediated Hepatic Gene Transfer in Rat Eliminates Beta-Galactosidase Transduced Hepatocytes but Does Not Prevent Expression in AAV-Transduced Muscles

, 2002

openalex   +1 more source

Baseline characteristics of contemporary trial participants with heart failure and reduced ejection fraction: The VICTOR trial

European Journal of Heart Failure, EarlyView.
Baseline characteristics for the vericiguat global study in participants with chronic heart failure (VICTOR) trial. ARNI, angiotensin receptor/neprilysin inhibitor; CRT, cardiac resynchronization therapy; eGFR, estimated glomerular filtration rate; GDMT, guideline‐directed medical therapy; HF, heart failure; HFrEF, heart failure with reduced ejection ...
Clara I. Saldarriaga, Faiez Zannad, Ciaran J. McMullan, Aiwen Xing, Davis Gates, Kevin J. Anstrom, Marc P. Bonaca, Stefano Corda, Justin A. Ezekowitz, Carolyn S.P. Lam, Eldrin F. Lewis, JoAnn Lindenfeld, Robert J. Mentz, Christopher O'Connor, Mahesh Patel, Piotr Ponikowski, Yogesh N.V. Reddy, Giuseppe M.C. Rosano, Michele Senni, James Udelson, Adriaan A. Voors, Javed Butler   +21 more
wiley   +1 more source

NEDD4L induces mitochondrial dysfunction and neurodegeneration by promoting LIPT2 degradation in Huntington's disease. [PDF]

Proc Natl Acad Sci U S A
Fan P, Liu Y, Liu C, Yao H, Xu S, Jiang Y, Wu Y, Liu Y, Guo X.   +8 more
europepmc   +1 more source

Finerenone, glycaemic status, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
Finerenone and glycaemic status in patients with heart failure with mildly reduced/preserved ejection fraction. CI, confidence interval; CV, cardiovascular; HF, heart failure; HR, hazard ratio; RR, rate ratio. Abstract Aims The efficacy and safety of the non‐steroidal mineralocorticoid receptor antagonist, finerenone, have not been examined in patients
Jawad H. Butt, Pardeep S. Jhund, Alasdair D. Henderson, Brian L. Claggett, Akshay S. Desai, Carolyn S.P. Lam, Meike Brinker, Patrick Schloemer, Prabhakar Viswanathan, Andrea Lage, Katja Rohwedder, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray   +18 more
wiley   +1 more source

A clinician's guide to AAV production - How manufacturing platforms shape vector properties. [PDF]

Med Genet
Magnus J, Käsbach J.
europepmc   +1 more source

Finerenone, chronic obstructive pulmonary disease, and heart failure with mildly reduced or preserved ejection fraction: A prespecified analysis of the FINEARTS‐HF trial

European Journal of Heart Failure, EarlyView.
The beneficial effects of finerenone in patients with heart failure (HF) and mildly reduced or preserved ejection fraction were consistent, regardless of a history of chronic obstructive pulmonary disease (COPD) status. BMI, body mass index; LVEF, left ventricular ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.
Jawad H. Butt, Pardeep S. Jhund, Alasdair D. Henderson, Brian L. Claggett, Akshay S. Desai, Carolyn S.P. Lam, Katharina Mueller, Markus F. Scheerer, Prabhakar Viswanathan, Michele Senni, Sanjiv J. Shah, Adriaan A. Voors, Faiez Zannad, Bertram Pitt, Muthiah Vaduganathan, Scott D. Solomon, John J.V. McMurray   +16 more
wiley   +1 more source

Protocol for CRISPR-based manipulation and visualization of endogenous α-synuclein in cultured mouse hippocampal neurons. [PDF]

STAR Protoc
Parra-Rivas LA, Sharma R, Rust TE, Bazick HO, Carlson-Stevermer J, Zylka MJ, Ogawa Y, Roy S.   +7 more
europepmc   +1 more source