Results 31 to 40 of about 46,714 (148)

AN OVERVIEW TO TURKEY-EU RELATIONS DURING THE JUSTICE AND DEVELOPMENT PARTY PERIOD

open access: yesSDÜ Vizyoner Dergisi, 2019
The Turkey–EU relations, which started in 1959, had passed through several important processes until today. Having achieved the status of a “candidate country” at the 1999 Helsinki Summit, Turkey started to make reforms to join the EU on 3 November 2002,
Selim Kanat   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression

open access: yesBiomedicines, 2020
Amyloid precursor protein (APP) is directly related to Aβ amyloidosis—a hallmark of Alzheimer’s disease (AD). However, the impact of environmental factors upon APP biology and Aβ amyloid pathology have not been well studied.
Xiaoyang Mou   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Avrupa Birliği Uyum Sürecinde Bölgesel Kalkınma Politikaları: Bölgesel Kalkınma Ajansları ve Türkiye Uygulaması

open access: yesAkademik İncelemeler Dergisi, 2014
1974’te Avrupa Bölgesel Kalkınma Fonlarının oluşturulmasından sonra zaman içerisinde şekillenen AB bölgesel politikaları 1990 sonrasında AB üyeliği için başvuruda bulunan ülkeler için üyelik öncesi uyum sürecinde ilerleme kaydedilmesi gereken ...
Aziz Tuncer, Bilal Eryılmaz
doaj  

Media Ownership Concentration and Pluralism In The European Union: An Assessment Within The Framework Of EMFA

open access: yesErciyes İletişim Dergisi
Media ownership concentration threatens media freedom and pluralism by enabling economic and political influence over editorial decisions and information flow.
Canan Özcan, Vedat Çakır
doaj   +1 more source

United Nations Convention on Law of Sea as a Mixed Treaty of EU: A headache for Turkey?

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2013
Avrupa Birliği tarafından akdedilmiş uluslararası anlaşmalar ve andlaşmalar acquis communautaire yani AB müktesebatının bir parçasını teşkil etmektedir.
Ulas Gündüzler
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Kitap Tanıtımı: Brexit Sonrası Birleşik Krallık ve AB'nin Geleceği

open access: yesEkonomi, Politika & Finans Araştırmaları Dergisi, 2017
Diğer Avrupa devletlerinin aksine vetolu ve sıkıntılı bir dönemin ardından Avrupa Birliğine giren İngiltere’nin 2016 yılında aldığı “Brexit” kararı, şüphesiz sadece İngiltere’de değil tüm Avrupa’da dengeleri değiştirecek bir olaylar zincirinin ...
Yusuf Ertuğral
doaj  

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