Results 51 to 60 of about 447,015 (283)
IAFOR Journal of Arts & Humanities, 2023 The Mahabharata (composed in Sanskrit sometime between 400 BC and 400 AD), is one of the two major Sanskrit epics of ancient India. It has been used as a source of inspiration for various literary, artistic, and cultural expressions, and its themes and ...
Abhirami S, Smrutisikta Mishra
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Pirineos: Revista de Ecología de Montaña, 1999 [es] Durante estos últimos 50 años ha tenido lugar un abandono de las masías y de los cultivos tradicionales en los Prepirineos catalanes. En este trabajo se han estudiado los cambios de usos del suelo desde los años 50 hasta la actualidad en una cuenca
J. M. Ubalde, J. Rius, R. M. Poch
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The Changes in Cropland Pattern Enhanced Carbon Storage in Northwest China
Agronomy, 2023 Northwest China has experienced dramatic changes in agricultural land area in recent years. The effects of these changes on carbon storage are unknown, and this ambiguity hinders land development policies related to carbon emissions.
Junqia Kong, Longfei Chen
doaj +1 more source
Using Sub-Optimal Plan Detection to Identify Commitment Abandonment in Discrete Environments
, 2020 Assessing whether an agent has abandoned a goal or is actively pursuing it is important when multiple agents are trying to achieve joint goals, or when agents commit to achieving goals for each other.
Meneguzzi, Felipe +2 more
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Modeling plan-form deltaic response to changes in fluvial sediment supply [PDF]
, 2012 This study focuses on the effects of changes in fluvial sediment supply on the plan-form shape of wave-dominated deltas. We apply a one-line numerical shoreline model to calculate shoreline evolution after (I) elimination and (II) time-periodic variation
Ashton, A.D. +4 more
core +3 more sources