Results 201 to 210 of about 441,962 (259)

Intralesional resection and autologous fibular graft reconstruction for a giant cell tumor of the fourth metacarpal with a secondary aneurysmal bone cyst: a case report. [PDF]

Int J Surg Case Rep
Khaiata H, Alabdullah H, Alhamid AAH, Daoud A, Youssef A.   +4 more
europepmc   +1 more source

Osseoperceptive EMG Feedback Improves Grasp Force Control in Myoelectric Prosthetic Hands

Advanced Science, EarlyView.
Osseoperception is explored as a non‐invasive pathway for delivering sensory feedback in myoelectric prosthetic control. By encoding the user's electromyographic (EMG) signal through bone‐conducted stimulation, this approach enables predictive grasp force regulation.
Cristian Felipe Blanco‐Diaz, Strahinja Dosen, Leonardo Cappello   +2 more
wiley   +1 more source

The prognostic value of DIC score combined with lactate in patients with cirrhosis complicated by variceal upper gastrointestinal bleeding: a single-center retrospective cohort study. [PDF]

Front Med (Lausanne)
Cui Y, Liu B, Geng N, Liu Z, Pan W, Li M, Lai CL, Miao Y, Wang J, Li H.   +9 more
europepmc   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Age-associated B cells predict coronary events in humans and aggravate murine atherosclerosis. [PDF]

Cardiovasc Res
de Mol J, Katra P, Smit V, Witteveen A, Tomas L, Andersson L, Engels SWM, Andersson S, Bernabé Kleijn MNA, Schiopu A, Bengtsson E, Bot I, Engelbertsen D, Kuiper J, Björkbacka H, Foks AC.   +15 more
europepmc   +1 more source

Similarity‐Enhanced Representation Learning of Non‐Canonical Amino Acids for Therapeutic Peptide Modeling

Advanced Science, EarlyView.
Non‐canonical amino acids (ncAAs) enhance peptide therapeutics but remain difficult to model computationally. SinCAA, a similarity‐enhanced pretraining framework, jointly optimizes contrastive learning guided by a novel conformational similarity metric with masked node reconstruction, capturing both functional relationships and chemical identity of ...
Chencheng Xu, Lesong Wei, Jianmin Wang, Yuanpeng Xiong, Ruochi Zhang, Yu Wang, Chao Zha, Qiangcheng Zeng, Xin Gao   +8 more
wiley   +1 more source

Single-cell multi-omics reveals circulating B cell heterogeneity across diverse disease contexts. [PDF]

Front Cell Dev Biol
Gan R, Zhong Y.
europepmc   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

The Developmental and Functional Implications of Age-Associated B Cells (ABCs) Across Tissue Microenvironments. [PDF]

Immunol Rev
Francis RL, Weinstein JS.
europepmc   +1 more source