Results 1 to 10 of about 30,780 (163)

Regulation of apoptosis by PML and the PML-NBs [PDF]

Oncogene, 2008
The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a variety of tumors. PML is essential for the proper assembly of a nuclear macromolecular structure called the PML nuclear body (PML-NB).
Rosa Bernardi, Antonella Papa, Pier Paolo Pandolfi   +2 more
exaly   +3 more sources

PML degradation: multiple ways to eliminate PML. [PDF]

Frontiers in Oncology, 2013
The promyelocytic leukemia gene (PML) critically regulates several cellular functions that oppose tumorigenesis such as oncogene-induced senescence, apoptosis, the response to DNA damage and to viral infections.
Andrea eRabellino, Pier Paolo eScaglioni
doaj   +3 more sources

Gene Expression of Promyelocytic Leukemia Proteins and IFN-γ Is Reduced in Rotavirus-Infected Children [PDF]

Iranian Biomedical Journal, 2020
Background: Rotavirus infection is one of the most common gastroenteritis in the world, and a million cases are registered to enter hospital every year.
Ahmed Jasim Mohammed, Zeenah Weheed Atwan, Aida Abdul-Kareem   +2 more
doaj   +3 more sources

Evidence for the effects of decommissioning man-made structures on marine ecosystems globally: a systematic map protocol

Environmental Evidence, 2021
Background Numerous man-made structures (MMS) have been installed in various parts of the ocean (e.g. oil and gas structures, offshore wind installations). Many are now at, or nearing, the end of their intended life.
Anaëlle J. Lemasson, Antony M. Knights, Murray Thompson, Gennadi Lessin, Nicola Beaumont, Christine Pascoe, Ana M. Queirós, Louise McNeill, Michaela Schratzberger, Paul J. Somerfield   +9 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy Associated to Multiple Sclerosis Therapies: Review of the literature [PDF]

Romanian Journal of Neurology, 2015
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection associated with the reactivation of the JC virus, causing a severe demyelination within the central nervous system in patients with immunosuppression caused by disease or ...
Ana-Maria Vladila, Dan-Andrei Mitrea, Sanda Maria Nica, Ioan Buraga   +3 more
doaj   +1 more source

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

Disease Models & Mechanisms, 2022
Paget's disease of bone (PDB) is characterized by focal increases in bone remodelling. Genome-wide association studies identified a susceptibility locus for PDB tagged by rs5742915, which is located within the PML gene.
Sachin Wani, Anna Daroszewska, Donald M. Salter, Rob J. van ‘t Hof, Stuart H. Ralston, Omar M. E. Albagha   +5 more
doaj   +1 more source

Regulation of NF-κB by PML and PML-RARα [PDF]

Scientific Reports, 2017
AbstractPromyelocytic Leukemia (PML) is a nuclear protein that forms sub-nuclear structures termed nuclear bodies associated with transcriptionally active genomic regions. PML is a tumour suppressor and regulator of cell differentiation. We demonstrate that PML promotes TNFα-induced transcriptional responses by promoting NF-κB activity.
Ahmed, Abrar, Wan, Xiaochun, Mitxitorena, Izaskun, Lindsay, Andrew J., Pandolfi, Pier Paolo, McCaffrey, Mary W., Keeshan, Karen, Chen, Youhai H., Carmody, Ruaidhri J.   +8 more
openaire   +3 more sources

Компьютерная симуляция распространения плоской электромагнитной волны в волноводе образованном поверхностью Земли и ионосферой при условии неоднородной проводимости границ

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2023
В статье приводятся результаты компьютерного моделирования распространения плоской электромагнитной волны. Грозовые разряды являются естественными источниками импульсного электромагнитного излучения (атмосферика).
Твёрдый, Д.А., Малкин, Е.И.   +1 more
doaj   +1 more source

Математическое моделирование распространения плоской электромагнитной волны в полосковом волноводе с неоднородной проводимостью границ

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2022
В статье проводится математическое моделирование электромагнитной динамики атмосферика. Атмосферик – широкополосный сигнал с максимумом интенсивности в диапазоне частот 8-10 кГц, который распространяется в виде плоской электромагнитной волны в сложной ...
Твёрдый, Д.А., Малкин, Е.И., Паровик, Р.И.   +2 more
doaj   +1 more source

Evidence for the effects of decommissioning man-made structures on marine ecosystems globally: a systematic map

Environmental Evidence, 2022
Background Many marine man-made structures (MMS), such as oil and gas platforms or offshore wind turbines, are nearing their ‘end-of-life’ and require decommissioning.
Anaëlle J. Lemasson, Paul J. Somerfield, Michaela Schratzberger, Caroline Louise McNeill, Joana Nunes, Christine Pascoe, Stephen C. L. Watson, Murray S. A. Thompson, Elena Couce, Antony M. Knights   +9 more
doaj   +1 more source