Results 11 to 20 of about 100,358 (268)
PML degradation: multiple ways to eliminate PML. [PDF]
Frontiers in Oncology, 2013 The promyelocytic leukemia gene (PML) critically regulates several cellular functions that oppose tumorigenesis such as oncogene-induced senescence, apoptosis, the response to DNA damage and to viral infections.
Andrea eRabellino, Pier Paolo eScaglioni
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Cold Spring Harbor Perspectives in Biology, 2010 PML nuclear bodies are matrix-associated domains that recruit an astonishing variety of seemingly unrelated proteins. Since their discovery in the early 1960s, PML bodies have fascinated cell biologists because of their beauty and their tight association with cellular disorders.
Lallemand-Breitenbach, Valérie +1 more
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PML, SUMOylation, and Senescence [PDF]
Frontiers in Oncology, 2013 Since its discovery, 25 years ago, promyelocytic leukemia (PML) has been an enigma. Implicated in the oncogenic PML/RARA fusion, forming elusive intranuclear domains, triggering cell death or senescence, controlled by and perhaps controlling SUMOylation… there are multiple PML-related issues.
Hugues eDe Thé +10 more
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Regulation of apoptosis by PML and the PML-NBs [PDF]
Oncogene, 2008 The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a variety of tumors. PML is essential for the proper assembly of a nuclear macromolecular structure called the PML nuclear body (PML-NB).
Bernardi R +2 more
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Perfectly Matched Layer in Numerical Wave Propagation: Factors that Affect its Performance [PDF]
, 2004 The perfectly matched layer (PML) boundary condition is generally employed to prevent spurious reflections from numerical boundaries in wave propagation methods. However, PML requires additional computational resources.
Banerjee +18 more
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A programme for risk assessment and minimisation of progressive multifocal leukoencephalopathy developed for vedolizumab clinical trials [PDF]
, 2018 Introduction Over the past decade, the potential for drug-associated progressive multifocal leukoencephalopathy (PML) has become an increasingly important consideration in certain drug development programmes, particularly those of immunomodulatory ...
Berger, Joseph R +12 more
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Журнал инфектологии, 2019 Progressive multifocal leukoencephalopathy (PML) is one of the most severe opportunistic diseases of the central nervous system, which leads to multiple demyelination of brain structures, neurological symptoms and frequent death or disability of the ...
E. A. Samotolkina +3 more
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Application of the Reflectionless Discrete Perfectly Matched Layer for Acoustic Wave Simulation
Frontiers in Earth Science, 2022 The perfectly matched layer (PML) is one of the most popular absorbing boundary conditions for simulating seismic waves. In theory, the PML can absorb incident waves at any incident angle and any frequency in a medium. However, numerical reflections will
Yingjie Gao +3 more
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Measuring the similarity of PML documents with RFID-based sensors [PDF]
, 2013 The Electronic Product Code (EPC) Network is an important part of the Internet of Things. The Physical Mark-Up Language (PML) is to represent and de-scribe data related to objects in EPC Network.
Reza, Malekian +4 more
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Viscoelastic modeling and factor Q for reflection data
Geofísica Internacional, 2012 Los modelos numéricos viscoelásticos, basados en el concepto de mecanismos de dispersión, toman en cuenta las variables de memoria y algunos parámetros de dispersión, a saber los tiempos de relajación de tensión. En la práctica de la geofísica, el factor
Vladimir Sabinin
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