Results 1 to 10 of about 1,606,785 (217)

Transcription Factor KLF14 and Metabolic Syndrome

Frontiers in Cardiovascular Medicine, 2020
Metabolic syndrome (MetSyn) is a combination of metabolic abnormalities that lead to the development of cardiovascular disease (CVD) and Type 2 Diabetes (T2D).
Qianyi Yang, Mete Civelek, Mete Civelek
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Human transcription factor protein interaction networks

Nature Communications, 2022
Transcription factors (TFs) interact with several other proteins in the process of transcriptional regulation. Here the authors identify 6703 and 1536 protein–protein interactions for 109 different human TFs through BioID and AP-MS analyses, respectively.
Helka Göös, Matias Kinnunen, Kari Salokas, Zenglai Tan, Xiaonan Liu, Leena Yadav, Qin Zhang, Gong-Hong Wei, Markku Varjosalo   +8 more
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Transcription factor EB regulates cardiovascular homeostasis

EBioMedicine, 2021
Cardiovascular diseases (CVDs) are the leading cause of death and a major cause of disability globally. Transcription factor EB (TFEB), as a member of the microphthalmia transcription factor (MITF) family, has been demonstrated to be a master regulator ...
Haocheng Lu, Jinjian Sun, Milton H. Hamblin, Y. Eugene Chen, Yanbo Fan   +4 more
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Optimization of Transcription Factor Genetic Circuits

Biology, 2022
Transcription factors (TFs) affect the production of mRNAs. In essence, the TFs form a large computational network that controls many aspects of cellular function. This article introduces a computational method to optimize TF networks. The method extends
Steven A. Frank
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SUMOylation of zebrafish transcription factor Zbtb21 affects its transcription activity [PDF]

PeerJ
Background Post-translational modification by Small Ubiquitin-like MOdifier (SUMO) is an important mechanism to regulate protein activity, protein stability, and localization of substrates.
Zhou Fang, Yun Deng, Haihong Wang, Jun Zhou   +3 more
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Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor

International Journal of Endocrinology, 2011
The zinc finger E-box binding protein 1 (ZEB1) transcription factor belongs to a two-member family of zinc-finger homeodomain proteins involved in physiological and pathological events mostly relating to cell migration and epithelial to mesenchymal ...
Bynthia M. Anose, Michel M. Sanders
doaj   +1 more source

Transcription Factor Binding to Replicated DNA

Cell Reports, 2020
Summary: Genome replication perturbs the DNA regulatory environment by displacing DNA-bound proteins, replacing nucleosomes, and introducing dosage imbalance between regions replicating at different S-phase stages.
Raz Bar-Ziv, Sagie Brodsky, Michal Chapal, Naama Barkai   +3 more
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NTH201, a Novel Class II KNOTTED1-Like Protein, Facilitates the Cell-to-Cell Movement of Tobacco mosaic virus in Tobacco

Molecular Plant-Microbe Interactions, 2008
NTH201, a novel class II KNOTTED1-like protein gene, was cloned from tobacco (Nicotiana tabacum cv. Xanthi) and its role in Tobacco mosaic virus (TMV) infection was analyzed. Virus-induced gene silencing of NTH201 caused a delay in viral RNA accumulation
Atsushi Yoshii, Takumi Shimizu, Akiko Yoshida, Koji Hamada, Keitaro Sakurai, Yasuyuki Yamaji, Masashi Suzuki, Shigetou Namba, Tadaaki Hibi   +8 more
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Activating transcription factor 4-dependent hsa-miR-663a transcription mediates mTORC1/p70S6K1 signaling underleucine deprivation

Frontiers in Nutrition, 2022
The mechanistic target of rapamycin complex 1 (mTORC1) is involved in nutrient-induced signaling and is a master regulator of cell growth and metabolism.
Junki Yamamura, Sihui Ma, Huijuan Jia, Hisanori Kato   +3 more
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Research progress of E2F1/7/8 in cervical cancer

生物医学转化
Transcription factor 1 (E2F1) is the most extensively studied member of the transcription factor E2F family. It is mainly involved in the regulation of the cell cycle, cell proliferation, and differentiation.
Du Mengmeng, Nie Xiazi, Wang Mei, Ma Xiaomei   +3 more
doaj   +1 more source