Results 1 to 10 of about 169 (168)

Eukaryotic transcription factors [PDF]

open access: yesBiochemical Journal, 1990
AbstractMany nuclear proteins have been found recently to interact with short conserved sequences which are involved in regulating the transcription of various genes. Nuclear transcription factors may be arbitrarily subdivided into two groups, ubiquitous and tissue‐specific.
O L, Polyanovsky, A G, Stepchenko
openaire   +4 more sources

The Transcription Factor Encyclopedia [PDF]

open access: yesGenome Biology, 2012
AbstractHere we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review articles on pertinent human, mouse and rat TFs.
Yusuf, Dimas   +114 more
openaire   +11 more sources

Transcription Factor Dynamics [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2021
To predict transcription, one needs a mechanistic understanding of how the numerous required transcription factors (TFs) explore the nuclear space to find their target genes, assemble, cooperate, and compete with one another. Advances in fluorescence microscopy have made it possible to visualize real-time TF dynamics in living cells, leading to two ...
Feiyue Lu, Timothée Lionnet
openaire   +2 more sources

Smad transcription factors [PDF]

open access: yesGenes & Development, 2005
Smad transcription factors lie at the core of one of the most versatile cytokine signaling pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent progress has shed light into the processes of Smad activation and deactivation, nucleocytoplasmic dynamics, and assembly of transcriptional complexes.
Joan, Massagué   +2 more
openaire   +2 more sources

Transcription factors in microcephaly

open access: yesFrontiers in Neuroscience, 2023
Higher cognition in humans, compared to other primates, is often attributed to an increased brain size, especially forebrain cortical surface area. Brain size is determined through highly orchestrated developmental processes, including neural stem cell proliferation, differentiation, migration, lamination, arborization, and apoptosis.
Youngshin Lim, Youngshin Lim
openaire   +3 more sources

The Human Transcription Factors [PDF]

open access: yesCell, 2018
Transcription factors (TFs) recognize specific DNA sequences to control chromatin and transcription, forming a complex system that guides expression of the genome. Despite keen interest in understanding how TFs control gene expression, it remains challenging to determine how the precise genomic binding sites of TFs are specified and how TF binding ...
Lambert, Samuel A.   +9 more
openaire   +5 more sources

Transcription factors in fungi [PDF]

open access: yesFEMS Microbiology Letters, 2008
Transcription factors (TFs) orchestrate gene expression control of a cell and, in many respects, their repertoire determines the life and functionality of the cell. For a better understanding of their regulatory mechanisms, it is essential to know the entire repertoire of TFs of a species.
openaire   +2 more sources

Transcription Factors in Cancer

open access: yesInternational Journal of Molecular Sciences, 2022
This Special Issue comprises three original studies and five review articles [...]
Tomasz Wilanowski, Sebastian Dworkin
openaire   +2 more sources

Transcription factors and asthma [PDF]

open access: yesEuropean Respiratory Journal, 1998
Asthma is characterized by the expression of multiple genes for inflammatory proteins, such as cytokines, enzymes, receptors and adhesion molecules. This is orchestrated by transcription factors, which are proteins that bind to the promoter regions of these genes and may be activated by inflammatory stimuli, such as cytokines.
P J, Barnes, I M, Adcock
openaire   +2 more sources

Deacetylation of Transcription Factors in Carcinogenesis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Reversible Nε-lysine acetylation/deacetylation is one of the most common post-translational modifications (PTM) of histones and non-histone proteins that is regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs). This epigenetic process is highly involved in carcinogenesis, affecting histone and non-histone proteins’ properties
Marta Halasa   +6 more
openaire   +3 more sources

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