Results 1 to 10 of about 1,457,371 (246)

Transcription factors in microcephaly

Frontiers in Neuroscience, 2023
Higher cognition in humans, compared to other primates, is often attributed to an increased brain size, especially forebrain cortical surface area. Brain size is determined through highly orchestrated developmental processes, including neural stem cell ...
Youngshin Lim, Youngshin Lim
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Triple-negative and triple-positive breast cancer cells reciprocally control their growth and migration via the S100A4 pathway

Cell Adhesion & Migration, 2022
The study’s aim was to investigate the S100A4-mediated mechanisms of the regulation of tumor cell proliferation and migration in the human triple-positive breast carcinoma cell line MCF-7 (TPBC) and triple-negative breast carcinoma cell line MDA-MB-231 ...
Elena A. Dukhanina, Tatiana N. Portseva, Alexander S. Dukhanin, Sofia G. Georgieva   +3 more
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A novel chromatin-remodeling complex variant, dcPBAF, is involved in maintaining transcription in differentiated neurons

Frontiers in Cell and Developmental Biology, 2023
The Polybromo-associated BAF (BRG1- or BRM-associated factors) (PBAF) chromatin-remodeling complex is essential for transcription in mammalian cells.
Nataliya V. Soshnikova, Nataliya V. Soshnikova, Nataliya V. Soshnikova, Asya M. Azieva, Asya M. Azieva, Nataliya S. Klimenko, Alvina I. Khamidullina, Alexey V. Feoktistov, Alexey V. Feoktistov, Andrey A. Sheynov, Alexander V. Brechalov, Victor V. Tatarskiy, Sofia G. Georgieva   +12 more
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Primate-specific stress-induced transcription factor POU2F1Z protects human neuronal cells from stress

Scientific Reports, 2021
The emergence of new primate-specific genes is an essential factor in human and primate brain development and functioning. POU2F1/Oct-1 is a transcription regulator in higher eukaryotes which is involved in the regulation of development, differentiation,
Alexander G. Stepchenko, Tatiana N. Portseva, Ivan A. Glukhov, Alina P. Kotnova, Bella M. Lyanova, Sofia G. Georgieva, Elizaveta V. Pankratova   +6 more
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Optimization of Cdx Transcription Factors Characteristics

Журнал інженерних наук, 2023
This study presents a new application of TOPSIS for the optimization of transcription factors characteristics. This application is essential as it can help compare the characteristics of these proteins and determine the optimized output of their ...
Javanbakht T.
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Eukaryotic transcription factors [PDF]

Biochemical Journal, 1990
AbstractMany nuclear proteins have been found recently to interact with short conserved sequences which are involved in regulating the transcription of various genes. Nuclear transcription factors may be arbitrarily subdivided into two groups, ubiquitous and tissue‐specific.
O L, Polyanovsky, A G, Stepchenko
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Insulin-Responsive Transcription Factors

Biomolecules, 2021
The hormone insulin executes its function via binding and activating of the insulin receptor, a receptor tyrosine kinase that is mainly expressed in skeletal muscle, adipocytes, liver, pancreatic β-cells, and in some areas of the central nervous system ...
Gerald Thiel, Lisbeth A. Guethlein, Oliver G. Rössler   +2 more
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Transcription factors organize into functional groups on the linear genome and in 3D chromatin

Heliyon, 2023
Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial ...
Rakesh Netha Vadnala, Sridhar Hannenhalli, Leelavati Narlikar, Rahul Siddharthan   +3 more
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The Transcription Factor Encyclopedia [PDF]

Genome Biology, 2012
AbstractHere we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review articles on pertinent human, mouse and rat TFs.
Yusuf, Dimas, Butland, Stefanie L., Swanson, Magdalena I., Bolotin, Eugene, Ticoll, Amy, Cheung, Warren A., Zhang, Xiao Yu Cindy, Dickman, Christopher T. D., Fulton, Debra L., Lim, Jonathan S., Schnabl, Jake M., Ramos, Oscar H. P., Vasseur-Cognet, Mireille, de Leeuw, Charles N., Simpson, Elizabeth M., Ryffel, Gerhart U., Lam, Eric W.-F., Kist, Ralf, Wilson, Miranda S. C., Marco-Ferreres, Raquel, Brosens, Jan J., Beccari, Leonardo L., Bovolenta, Paola, Benayoun, Bérénice A., Monteiro, Lara J, Schwenen, Helma D C, Grontved, Lars, Wederell, Elizabeth, Mandrup, Susanne, Veitia, Reiner A, Chakravarthy, Harini, Hoodless, Pamela A., Mancarelli, M Michela, Torbett, Bruce E, Banham, Alison H, Reddy, Sekhar P, Cullum, Rebecca L, Liedtke, Michaela, Tschan, Mario P, Vaz, Michelle, Rizzino, Angie, Zannini, Mariastella, Frietze, Seth, Farnham, Peggy J, Eijkelenboom, Astrid, Brown, Philip J, Laperrière, David, Leprince, Dominique, de Cristofaro, Tiziana, Prince, Kelly L, Putker, Marrit, del Peso, Luis, Camenisch, Gieri, Wenger, Roland H, Mikula, Michal, Rozendaal, Marieke, Mader, Sylvie, Ostrowski, Jerzy, Rhodes, Simon J, Van Rechem, Capucine, Boulay, Gaylor, Olechnowicz, Sam W Z, Breslin, Mary B, Lan, Michael S, Nanan, Kyster K, Wegner, Michael, Hou, Juan, Mullen, Rachel D, Colvin, Stephanie C, Noy, Peter John, Webb, Carol F, Witek, Matthew E, Ferrell, Scott, Daniel, Juliet M, Park, Jason, Waldman, Scott A, Peet, Daniel J, Taggart, Michael, Jayaraman, Padma-Sheela, Karrich, Julien J, Blom, Bianca, Vesuna, Farhad, O'Geen, Henriette, Sun, Yunfu, Gronostajski, Richard M, Woodcroft, Mark W, Hough, Margaret R, Chen, Edwin, Europe-Finner, G Nicholas, Karolczak-Bayatti, Magdalena, Bailey, Jarrod, Hankinson, Oliver, Raman, Venu, LeBrun, David P, Biswal, Shyam, Harvey, Christopher J, DeBruyne, Jason P, Hogenesch, John B, Hevner, Robert F, Héligon, Christophe, Luo, Xin M, Blank, Marissa Cathleen, Millen, Kathleen Joyce, Sharlin, David S, Forrest, Douglas, Dahlman-Wright, Karin, Zhao, Chunyan, Mishima, Yuriko, Sinha, Satrajit, Chakrabarti, Rumela, Portales-Casamar, Elodie, Sladek, Frances M, Bradley, Philip H, Wasserman, Wyeth W, Cindy Zhang, Xiao   +114 more
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Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]

PeerJ, 2023
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot, Felippe José Almeida Loureiro, Giordanna Pereira Chemelo, Ricardo Alves Mesquita, Aline Maria Pereira Cruz Ramos, Rommel Thiago Jucá Ramos, Artur Luiz da Costa da Silva, Sílvio Augusto Fernandes de Menezes, Maria Sueli da Silva Kataoka, Sergio de Melo Alves Junior, João de Jesus Viana Pinheiro   +10 more
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