Results 41 to 50 of about 9,751,730 (314)

Smad transcription factors [PDF]

Genes & Development, 2005
Smad transcription factors lie at the core of one of the most versatile cytokine signaling pathways in metazoan biology—the transforming growth factor-β (TGFβ) pathway. Recent progress has shed light into the processes of Smad activation and deactivation, nucleocytoplasmic dynamics, and assembly of transcriptional complexes.
Joan, Massagué, Joan, Seoane, David, Wotton   +2 more
openaire   +2 more sources

A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]

, 2013
A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J., Jonathan D. Moore, Laura Bowden, Katherine J. Denby, Hickman, Richard J., Beynon, Jim, Richard Hickman, Findlay Bewicke‐Copley, David L. Wild, Vicky Buchanan‐Wollaston, Jim Beynon, Jackson, Alison C., Denby, Katherine J., Mead, A. (Andrew), Penfold, Christopher A., Bowden, Laura, Andrew Mead, Wild, David L., Christopher A. Penfold, Moore, Jonathan D., Emily Breeze, Breeze, Emily, Alison Jackson, Sascha Ott, Buchanan-Wollaston, Vicky, Peijun Zhang, Emma Cooke, Hill, C., Zhang, Peijun, Bewicke-Copley, Findlay, Claire Hill, Ott, Sascha, Moore, J.D., Bewick-Copley, F., Wild, D.L., Jackson, A., Bowden, L., Ott, S., Breeze, E., Cooke, E., Zhang, P., Penfold, C.A., Buchanan-Wollaston, V., Hickman, R., Mead, A., Beynon, J., Denby, K.J.   +46 more
core   +1 more source

Transcription factors underlying photoreceptor diversity

eLife, 2023
During development, retinal progenitors navigate a complex landscape of fate decisions to generate the major cell classes necessary for proper vision. Transcriptional regulation is critical to generate diversity within these major cell classes.
Juan M Angueyra, Vincent P Kunze, Laura K Patak, Hailey Kim, Katie Kindt, Wei Li   +5 more
doaj   +1 more source

Hypoxia-Inducible Factor-1α (HIF-1α) Potentiates β-Cell Survival after Islet Transplantation of Human and Mouse Islets

Cell Transplantation, 2013
A high proportion of β-cells die within days of islet transplantation. Reports suggest that induction of hypoxia-inducible factor-1α (HIF-1α) predicts adverse transplant outcomes.
Rebecca A. Stokes, Kim Cheng, Natasha Deters, Sue Mei Lau, Wayne J. Hawthorne, Philip J. O'connell, Jessica Stolp, Shane Grey, Thomas Loudovaris, Thomas W. Kay, Helen E. Thomas, Frank J. Gonzalez, Jenny E. Gunton   +12 more
doaj   +1 more source

Falling for the dark side of transcription: Nab2 fosters RNA polymerase III transcription. [PDF]

, 2016
RNA polymerase III (RNAPIII) synthesizes diverse, small, non-coding RNAs with many important roles in the cellular metabolism. One of the open questions of RNAPIII transcription is whether and how additional factors are involved.
Reuter, LM, Sträßer, K
core   +1 more source

Transcription factors in fungi [PDF]

FEMS Microbiology Letters, 2008
Transcription factors (TFs) orchestrate gene expression control of a cell and, in many respects, their repertoire determines the life and functionality of the cell. For a better understanding of their regulatory mechanisms, it is essential to know the entire repertoire of TFs of a species.
openaire   +2 more sources

Transposon-derived transcription factors across metazoans

Frontiers in Cell and Developmental Biology, 2023
Transposable elements (TE) could serve as sources of new transcription factors (TFs) in plants and some other model species, but such evidence is lacking for most animal lineages. Here, we discovered multiple independent co-options of TEs to generate 788 
Krishanu Mukherjee, Leonid L. Moroz, Leonid L. Moroz   +2 more
doaj   +1 more source

Turnover and function of DNA methylation at transcription factor binding sites [PDF]

, 2014
Cell type identity is largely determined by regulatory networks consistent of various transcription factors. Transcription factor activity requires interaction with DNA and thus critically depends on the accessibility of binding motifs.
Feldmann, Angelika
core   +1 more source

Fungal CSL transcription factors

BMC Genomics, 2007
Background The CSL (CBF1/RBP-Jκ/Suppressor of Hairless/LAG-1) transcription factor family members are well-known components of the transmembrane receptor Notch signaling pathway, which plays a critical role in metazoan development.
Folk Petr, Půta František, Převorovský Martin   +2 more
doaj   +1 more source

Human naive CD8 T cells down-regulate expression of the WNT pathway transcription factors lymphoid enhancer binding factor 1 and transcription factor 7 (T cell factor-1) following antigen encounter in vitro and in vivo [PDF]

, 2006
The transcription factors lymphoid enhancer binding factor 1 (LEF1) and transcription factor 7 (TCF7) (T cell factor-1 (TCF-1)) are downstream effectors of the WNT signaling pathway, which is a critical regulator of T cell development in the thymus.
Freeman, Tom, Herbert, Mark, Hasegawa, Hitoshi, Willinger, Tim, Callan, Margaret F C, McMichael, Andrew J   +5 more
core   +1 more source