Results 31 to 40 of about 1,457,371 (246)
Transcription Factors in Cancer
International Journal of Molecular Sciences, 2022 This Special Issue comprises three original studies and five review articles [...]
Tomasz Wilanowski, Sebastian Dworkin
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Hsp90 the concertmaster: tuning transcription
Frontiers in Oncology, 2015 In the last decade Hsp90 has emerged as a major regulator of cancer cell growth and proliferation. In cancer cells, it assists in giving maturation to oncogenic proteins including several kinases and transcription factors.
Nidhi eKhurana, Sunanda eBhattacharyya
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Sweet Melody or Jazz? Transcription Around DNA Double-Strand Breaks
Frontiers in Molecular Biosciences, 2021 Genomic integrity is continuously threatened by thousands of endogenous and exogenous damaging factors. To preserve genome stability, cells developed comprehensive DNA damage response (DDR) pathways that mediate the recognition of damaged DNA lesions ...
Qilin Long +2 more
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Transcription factors and asthma [PDF]
European Respiratory Journal, 1998 Asthma is characterized by the expression of multiple genes for inflammatory proteins, such as cytokines, enzymes, receptors and adhesion molecules. This is orchestrated by transcription factors, which are proteins that bind to the promoter regions of these genes and may be activated by inflammatory stimuli, such as cytokines.
P J, Barnes, I M, Adcock
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
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Microbiology, 2008 Gene expression is a fundamental process that is highly conserved from humans to bacteria. The first step in gene expression, transcription, is performed by structurally conserved DNA-dependent RNA polymerases (RNAPs), which results in the synthesis of an RNA molecule from a DNA template.
Lewis, P. J., Doherty, G. P., Clarke, J.
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
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ASSIST: Refinement of a Benefits Navigator Intervention Among Low‐Income Pediatric Oncology Families
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background/Objectives Children with cancer living in poverty experience worse survival and quality of life. Interventions connecting low‐income families to benefits (e.g., Supplemental Nutrition Assistance Program [SNAP] improve health outcomes; yet nearly 50% of SNAP‐eligible pediatric oncology families are unenrolled.
Puja J. Umaretiya +11 more
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Frontiers in Immunology, 2015 Splenic transitional B-cells (T1 and T2) are selected to avoid self-reactivity and to safeguard against autoimmunity, then differentiate into mature follicular (FO-I and FO-II) and marginal zone (MZ) subsets.
Eden eKleiman +14 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
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