Results 21 to 30 of about 2,373,012 (300)

Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

open access: yeseLife, 2022
For over 40 years, the Bicoid-hunchback (Bcd-hb) system in the fruit fly embryo has been used as a model to study how positional information in morphogen concentration gradients is robustly translated into step-like responses.
Gonçalo Fernandes   +8 more
doaj   +1 more source

Evolution of Developmental GATA Factors in Nematodes

open access: yesJournal of Developmental Biology, 2020
GATA transcription factors are found in animals, plants, and fungi. In animals, they have important developmental roles in controlling specification of cell identities and executing tissue-specific differentiation.
Ethan Eurmsirilerd, Morris F. Maduro
doaj   +1 more source

Transcriptional Regulation: a Genomic Overview [PDF]

open access: yes, 2002
The availability of the Arabidopsis thaliana genome sequence allows a comprehensive analysis of transcriptional regulation in plants using novel genomic approaches and methodologies. Such a genomic view of transcription first necessitates the compilation
Riechmann, José Luis
core   +2 more sources

A global function for transcription factors in assisting RNA polymerase II termination. [PDF]

open access: yes, 2017
The role of transcription factors (TFs) on nucleosome positioning, RNA polymerase recruitment, and transcription initiation has been extensively characterized.
Chanfreau, Guillaume F, Roy, Kevin
core   +1 more source

TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle [PDF]

open access: yes, 2016
Transcription is an intrinsically dynamic process and requires the coordinated interplay of RNA polymerases (RNAPs) with nucleic acids and transcription factors.
Gietl, Andreas   +5 more
core   +1 more source

The Transcription Factor Encyclopedia [PDF]

open access: yesGenome Biology, 2012
AbstractHere we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration. Our consortium of over 100 researchers has collectively contributed over 130 mini review articles on pertinent human, mouse and rat TFs.
Yusuf, Dimas   +114 more
openaire   +13 more sources

The T-cell oncogene Tal2 is a Target of PU.1 and upregulated during osteoclastogenesis [PDF]

open access: yes, 2013
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in the
Courtial, Nadine   +5 more
core   +5 more sources

Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

open access: yesScientific Reports, 2017
The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as
Victor V. Tatarskiy   +5 more
doaj   +1 more source

Transcription Factors in Alkaloid Engineering

open access: yesBiomolecules, 2021
Plants produce a large variety of low-molecular-weight and specialized secondary compounds. Among them, nitrogen-containing alkaloids are the most biologically active and are often used in the pharmaceutical industry. Although alkaloid chemistry has been
Yasuyuki Yamada, Fumihiko Sato
doaj   +1 more source

Thyroid-specific transcription factors control Hex promoter activity [PDF]

open access: yes, 2003
The homeobox-containing gene Hex is expressed in several cell types, including thyroid follicular cells, in which it regulates the transcription of tissue-specific genes. In this study the regulation of Hex promoter activity was investigated.
A. V., D'Elia   +9 more
core   +1 more source

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