Results 21 to 30 of about 9,355,994 (306)
Transcription Factor Dynamics [PDF]
To predict transcription, one needs a mechanistic understanding of how the numerous required transcription factors (TFs) explore the nuclear space to find their target genes, assemble, cooperate, and compete with one another. Advances in fluorescence microscopy have made it possible to visualize real-time TF dynamics in living cells, leading to two ...
Feiyue Lu, Timothée Lionnet
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Evolution of Developmental GATA Factors in Nematodes
GATA transcription factors are found in animals, plants, and fungi. In animals, they have important developmental roles in controlling specification of cell identities and executing tissue-specific differentiation.
Ethan Eurmsirilerd, Morris F. Maduro
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Recent advances in the structural molecular biology of Ets transcription factors: interactions, interfaces and inhibition. [PDF]
The Ets family of eukaryotic transcription factors is based around the conserved Ets DNA-binding domain. Although their DNA-binding selectivity is biochemically and structurally well characterized, structures of homodimeric and ternary complexes point to
Gileadi, Opher +8 more
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MIRTFnet: analysis of miRNA regulated transcription factors. [PDF]
Several expression datasets of miRNA transfection experiments are available to analyze the regulatory mechanisms downstream of miRNA effects. The miRNA induced regulatory effects can be propagated via transcription factors (TFs).
Küffner, Robert +11 more
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The Human Transcription Factors [PDF]
Transcription factors (TFs) recognize specific DNA sequences to control chromatin and transcription, forming a complex system that guides expression of the genome. Despite keen interest in understanding how TFs control gene expression, it remains challenging to determine how the precise genomic binding sites of TFs are specified and how TF binding ...
Lambert, Samuel A. +9 more
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Transcription Factors in Alkaloid Engineering
Plants produce a large variety of low-molecular-weight and specialized secondary compounds. Among them, nitrogen-containing alkaloids are the most biologically active and are often used in the pharmaceutical industry. Although alkaloid chemistry has been
Yasuyuki Yamada, Fumihiko Sato
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Nucleosome-mediated cooperativity between transcription factors [PDF]
Cooperative binding of transcription factors (TFs) to cis-regulatory regions (CRRs) is essential for precision of gene expression in development and other processes.
Leonid A. Mirny, Mirny, Leonid A
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The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as
Victor V. Tatarskiy +5 more
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A local regulatory network around three NAC transcription factors in stress responses and senescence in Arabidopsis leaves [PDF]
A model is presented describing the gene regulatory network surrounding three similar NAC transcription factors that have roles in Arabidopsis leaf senescence and stress responses. ANAC019, ANAC055 and ANAC072 belong to the same clade of NAC domain genes
Cooke, Emma J. +31 more
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CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks [PDF]
Baumbach J, Brinkrolf K, Czaja LF, Rahmann S, Tauch A. CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. BMC Genomics.
Baumbach Jan +9 more
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