Results 21 to 30 of about 46,902 (263)

The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption

open access: yesDisease Models & Mechanisms, 2022
Paget's disease of bone (PDB) is characterized by focal increases in bone remodelling. Genome-wide association studies identified a susceptibility locus for PDB tagged by rs5742915, which is located within the PML gene.
Sachin Wani   +5 more
doaj   +1 more source

Компьютерная симуляция распространения плоской электромагнитной волны в волноводе образованном поверхностью Земли и ионосферой при условии неоднородной проводимости границ

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2023
В статье приводятся результаты компьютерного моделирования распространения плоской электромагнитной волны. Грозовые разряды являются естественными источниками импульсного электромагнитного излучения (атмосферика).
Твёрдый, Д.А.   +1 more
doaj   +1 more source

Progressive Multifocal Leukoencephalopathy Associated to Multiple Sclerosis Therapies: Review of the literature [PDF]

open access: yesRomanian Journal of Neurology, 2015
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection associated with the reactivation of the JC virus, causing a severe demyelination within the central nervous system in patients with immunosuppression caused by disease or ...
Ana-Maria Vladila   +3 more
doaj   +1 more source

Математическое моделирование распространения плоской электромагнитной волны в полосковом волноводе с неоднородной проводимостью границ

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2022
В статье проводится математическое моделирование электромагнитной динамики атмосферика. Атмосферик – широкополосный сигнал с максимумом интенсивности в диапазоне частот 8-10 кГц, который распространяется в виде плоской электромагнитной волны в сложной ...
Твёрдый, Д.А.   +2 more
doaj   +1 more source

PML isoforms in response to arsenic: high-resolution analysis of PML body structure and degradation [PDF]

open access: yes, 2014
Arsenic is a clinically effective treatment for acute promyelocytic leukaemia (APL) in which the promyelocytic leukaemia (PML) protein is fused to retinoic receptor alpha (RARα).
Hands, K.J.   +7 more
core   +1 more source

Viscoelastic modeling and factor Q for reflection data

open access: yesGeofísica Internacional, 2012
Los modelos numéricos viscoelásticos, basados en el concepto de mecanismos de dispersión, toman en cuenta las variables de memoria y algunos parámetros de dispersión, a saber los tiempos de relajación de tensión. En la práctica de la geofísica, el factor
Vladimir Sabinin
doaj   +1 more source

ALIGNMENT OF HYPERSPECTRAL IMAGERY AND FULL-WAVEFORM LIDAR DATA FOR VISUALISATION AND CLASSIFICATION PURPOSES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The overarching aim of this paper is to enhance the visualisations and classifications of airborne remote sensing data for remote forest surveys. A new open source tool is presented for aligning hyperspectral and full-waveform LiDAR data.
M. Miltiadou   +3 more
doaj   +1 more source

Is PML a Tumor Suppressor? [PDF]

open access: yesFrontiers in Oncology, 2013
The role of the promyelocytic leukemia (PML) protein has been widely tested in many different contexts, as attested by the hundreds of papers present in the literature. In most of these studies, PML is regarded as a tumor suppressor, a notion on the whole accepted by the scientific community.
M. Mazza, P.G. Pelicci
openaire   +3 more sources

Targeting the acute promyelocytic leukemia-associated fusion proteins PML/RARα and PLZF/RARα with interfering peptides [PDF]

open access: yes, 2012
In acute promyelocytic leukemia (APL), hematopoietic differentiation is blocked and immature blasts accumulate in the bone marrow and blood. APL is associated with chromosomal aberrations, including t(15;17) and t(11;17).
Sabine Beez (123610)   +8 more
core   +1 more source

Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. [PDF]

open access: yes, 2011
The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expression.
Baiker Armin   +28 more
core   +2 more sources

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