Results 41 to 50 of about 42,451 (299)
The Role of Promyelocytic Leukemia Nuclear Bodies During HPV Infection
Frontiers in Cellular and Infection Microbiology, 2020 Promyelocytic leukemia (PML) nuclear bodies (NBs) are highly dynamic subnuclear structures. Their name giving major component, PML protein, is essential for their formation.
Lucile G. Guion +3 more
doaj +1 more source
Role of PML and PML-RARα in Mad-Mediated Transcriptional Repression [PDF]
Molecular Cell, 2001 Fusion of the promyelocytic leukemia (PML) protein to the retinoic acid receptor-alpha (RARalpha) generates the transforming protein of acute promyelocytic leukemias. PML appears to be involved in multiple functions, including apoptosis and transcriptional activation by RAR, whereas PML-RARalpha blocks these functions of PML. However, the mechanisms of
Khan, Md Matiullah +9 more
openaire +2 more sources
, 2014 The tumour suppressor PML (promyelocytic leukaemia protein) regulates several cellular pathways involving cell growth, apoptosis, differentiation and senescence.
Regad, T +6 more
core +1 more source
Pemodelan Awal Ground Penetrating Radar dengan Metode Discontinuous Galerkin dan PML Berenger
Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2016 This paper discusses the development of Discontinuous Galerkin method, which has both linear shape function and weight function, for modeling Ground Penetrating Radar (GPR) in heterogeneous media.
Pranowo
doaj +1 more source
Requirement of PML SUMO interacting motif for RNF4- or arsenic trioxide-induced degradation of nuclear PML isoforms. [PDF]
PLoS ONE, 2012 PML, the organizer of nuclear bodies (NBs), is expressed in several isoforms designated PMLI to VII which differ in their C-terminal region due to alternative splicing of a single gene.
Mohamed Ali Maroui +5 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Promyelocytic leukemia nuclear bodies (PML NBs) are multi-protein assemblies representing distinct sub-nuclear structures. As phase-separated molecular condensates, PML NBs exhibit liquid droplet-like consistency.
Upayan Patra, Stefan Müller
doaj +1 more source
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Preparation of LaB6 Powders via Calciothermic Reduction using Mechanochemistry and Acid Leaching
KONA Powder and Particle Journal, 2015 This study reports a room temperature mechanochemical route for the synthesis of LaB6 powders originated from related metal oxide powders as La2O3 and B2O3.
Duygu Ağaoğulları +3 more
doaj +1 more source
A Role for PML in Innate Immunity [PDF]
Genes & Cancer, 2011 The promyelocytic leukemia gene (PML) of acute promyelocytic leukemia is an established tumor suppressor gene with critical functions in growth suppression, induction of apoptosis, and cellular senescence. Interestingly, although less studied, PML seems to play a key role also in immune response to viral infection.
Lunardi A +15 more
openaire +7 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source